Oxytocin use in grand-multiparous patients: Safety and complications

Z. Ben-Aroya, D. Yochai, T. Silberstein, M. Friger, M. Hallak, M. Katz, M. Mazor

Research output: Contribution to journalArticlepeer-review

10 Scopus citations


Objective: To determine whether the use of oxytocin for the augmentation of labor in grandmultiparous women increases the risk of peripartum complications. Study design: During the years 1989-97, 11 075 grand-multiparous women delivered at our institution. In 424 grand-multiparous women, intravenous oxytocin was used for augmentation of labor. The control group consisted of the other 10 651 grand-multiparous women. All women were monitored for fetal heart rate and uterine contractions. We compared the rates of maternal and perinatal complications in these two groups by using x2 analysis and Fisher's exact test when appropriate. Results: No significant differences were found between the oxytocin and the control groups in the rates of placental abruption, intrapartum fetal death, postpartum hemorrhage, uterine rupture, fetal distress, meconium-stained amniotic fluid, an Apgar score of less than 7 at 5 min, Cesarean section, retained placenta and vaginal and cervical lacerations. In contrast, a significant increase in the rate of vacuum deliveries was observed in patients given oxytocin as compared to controls (3.5% vs. 1.4%, respectively; p = 0.001). Conclusions: The use of oxytocin in the grand-multiparous parturient was a safe procedure with no significant increase in peripartum complications. However, a higher rate of vacuum deliveries was found.

Original languageEnglish
Pages (from-to)328-331
Number of pages4
JournalJournal of Maternal-Fetal Medicine
Issue number5
StatePublished - 1 Jan 2001


  • Grand-multiparous women
  • Labor management
  • Oxytocin
  • Peripartum complications

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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