p53 mutations and inflammation-associated cancer are linked through TNF Signaling

Tomer Cooks, Curtis C. Harris

Research output: Contribution to journalShort surveypeer-review

14 Scopus citations

Abstract

In this issue, Di Minin etal. (2014) link mutant p53 and chronic inflammation to tumorigenic progression viaTNF signaling. Mutp53 interacts with the tumor suppressor DAB2IP in the cytoplasm, and induces a TNF-dependent transcriptional profile via NF-kB and JNK. In this issue, Di Minin etal. (2014) link mutant p53 and chronic inflammation to tumorigenic progression via TNF signaling. Mutp53 interacts with the tumor suppressor DAB2IP in the cytoplasm, and induces a TNF-dependent transcriptional profile via NF-kB and JNK.

Original languageEnglish
Pages (from-to)611-612
Number of pages2
JournalMolecular Cell
Volume56
Issue number5
DOIs
StatePublished - 4 Dec 2014
Externally publishedYes

ASJC Scopus subject areas

  • Molecular Biology
  • Cell Biology

Fingerprint

Dive into the research topics of 'p53 mutations and inflammation-associated cancer are linked through TNF Signaling'. Together they form a unique fingerprint.

Cite this