Abstract
The antiphospholipid syndrome (APS) is characterized by the presence of pathogenic autoantibodies against β2-glycoprotein-I (β2GPI). Studies of experimental APS models emphasized that molecular mimicry between β2GPI related synthetic peptides and structures within bacteria, viruses, tetanus toxoid, and cytomegalovirus as a cause for experimental APS. In this review we discuss the association of antiphospholipid antibodies with infectious agents, molecular mimicry as a proposed cause for development of APS, and the contribution of database to this topic.
Original language | English |
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Pages (from-to) | 142-145 |
Number of pages | 4 |
Journal | Progressi in Reumatologia |
Volume | 5 |
Issue number | 2 |
State | Published - 8 Nov 2004 |
Externally published | Yes |
Keywords
- Antiphospholipid syndrome
- Infection
- Thrombosis
ASJC Scopus subject areas
- Rheumatology