Pathological fracture of the mandible in a paediatric patient with congenital insensitivity to pain with anhidrosis (CIPA)

Esther Manor, Ben Zion Joshua, Jacov Levy, Peter A. Brennan, Lipa Bodner

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Congenital insensitivity to pain with anhidrosis (CIPA) is a rare hereditary sensory and autonomic neuropathy (HSAN) characterized by pain, self-mutilating behaviour, anhidrosis and recurrent hyperthermia. CIPA has a multisystem involvement, including fractures of the extremities with slow healing, immunologic abnormalities, and a chronic inflammatory state. The mandible is reported to have a higher incidence of osteomyelitis, though mandibular fracture among CIPA patients, is very rare, with to our knowledge no reports in children. A case of pathological fracture of the mandible in a 6-year-old child with CIPA treated by ORIF is reported. In contrast to the slow healing reported in long bones, the mandible healed very quickly, possibly indicating that the osteoporotic mandible in this group of patients is different from that seen in the elderly. Furthermore, the standard ORIF technique can be safely used in this rare group.

Original languageEnglish
Pages (from-to)e39-e41
JournalJournal of Cranio-Maxillo-Facial Surgery
Volume41
Issue number2
DOIs
StatePublished - 1 Mar 2013

Keywords

  • Bone healing
  • CIPA-congenital
  • Mandible
  • Open reduction
  • Pain with anhidrosis
  • Pathological fracture

ASJC Scopus subject areas

  • Surgery
  • Oral Surgery
  • Otorhinolaryngology

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