Percutaneous core needle biopsy in the diagnosis of mediastinal tumors

Joel Greif; Alexander N. Staroselsky; Moshe Gernjac; Yehuda Schwarz; Silvia Marmur; Marina Perlsman; Alon Yellin

doi:10.1016/S0169-5002(99)00053-7

Percutaneous core needle biopsy in the diagnosis of mediastinal tumors

Joel Greif, Alexander N. Staroselsky, Moshe Gernjac, Yehuda Schwarz, Silvia Marmur, Marina Perlsman, Alon Yellin

Research output: Contribution to journal › Article › peer-review

38 Scopus citations

Abstract

Objective: to determine the contribution of percutaneous core cutting needle biopsy (PCNB) in the diagnosis of mediastinal tumors. Design: retrospective review of 70 patients with mediastinal lesions who underwent CT-guided PCNB between 1988 and 1996. Results: PCNB provided adequate material in 62/70 cases, giving a total sample rate of 88.6%. Of these 62 patients, 57 were diagnosed correctly by PCNB whereas 5/62 were misdiagnosed as nonspecific inflammation, providing an overall sensitivity of 91.9%. PCNB established a specific histologic diagnosis in 90.3% of the patients, mainly in cases of lymphoma, bronchogenic carcinoma, and thymoma. Pneumothorax was the most commonly encountered complication (11%). Hemoptysis (30-50ml) occurred in only one (1.6%) of the patients. Conclusion: CT guided PCNB is an easy and safe procedure which can provide a precise diagnosis in the majority of mediastinal tumors and can obviate the need for exploratory thoracic surgery in cases which are medically treatable or non-resectable. Copyright (C) 1999 Elsevier Science Ireland Ltd.

Original language	English
Pages (from-to)	169-173
Number of pages	5
Journal	Lung Cancer
Volume	25
Issue number	3
DOIs	https://doi.org/10.1016/S0169-5002(99)00053-7
State	Published - 1 Sep 1999
Externally published	Yes

Keywords

Mediastinal lesions
Percutaneous cutting needle biopsy
Pneumothorax

ASJC Scopus subject areas

Oncology
Pulmonary and Respiratory Medicine
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/S0169-5002(99)00053-7

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title = "Percutaneous core needle biopsy in the diagnosis of mediastinal tumors",

abstract = "Objective: to determine the contribution of percutaneous core cutting needle biopsy (PCNB) in the diagnosis of mediastinal tumors. Design: retrospective review of 70 patients with mediastinal lesions who underwent CT-guided PCNB between 1988 and 1996. Results: PCNB provided adequate material in 62/70 cases, giving a total sample rate of 88.6%. Of these 62 patients, 57 were diagnosed correctly by PCNB whereas 5/62 were misdiagnosed as nonspecific inflammation, providing an overall sensitivity of 91.9%. PCNB established a specific histologic diagnosis in 90.3% of the patients, mainly in cases of lymphoma, bronchogenic carcinoma, and thymoma. Pneumothorax was the most commonly encountered complication (11%). Hemoptysis (30-50ml) occurred in only one (1.6%) of the patients. Conclusion: CT guided PCNB is an easy and safe procedure which can provide a precise diagnosis in the majority of mediastinal tumors and can obviate the need for exploratory thoracic surgery in cases which are medically treatable or non-resectable. Copyright (C) 1999 Elsevier Science Ireland Ltd.",

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author = "Joel Greif and Staroselsky, {Alexander N.} and Moshe Gernjac and Yehuda Schwarz and Silvia Marmur and Marina Perlsman and Alon Yellin",

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AU - Greif, Joel

AU - Staroselsky, Alexander N.

AU - Gernjac, Moshe

AU - Schwarz, Yehuda

AU - Marmur, Silvia

AU - Perlsman, Marina

AU - Yellin, Alon

PY - 1999/9/1

Y1 - 1999/9/1

N2 - Objective: to determine the contribution of percutaneous core cutting needle biopsy (PCNB) in the diagnosis of mediastinal tumors. Design: retrospective review of 70 patients with mediastinal lesions who underwent CT-guided PCNB between 1988 and 1996. Results: PCNB provided adequate material in 62/70 cases, giving a total sample rate of 88.6%. Of these 62 patients, 57 were diagnosed correctly by PCNB whereas 5/62 were misdiagnosed as nonspecific inflammation, providing an overall sensitivity of 91.9%. PCNB established a specific histologic diagnosis in 90.3% of the patients, mainly in cases of lymphoma, bronchogenic carcinoma, and thymoma. Pneumothorax was the most commonly encountered complication (11%). Hemoptysis (30-50ml) occurred in only one (1.6%) of the patients. Conclusion: CT guided PCNB is an easy and safe procedure which can provide a precise diagnosis in the majority of mediastinal tumors and can obviate the need for exploratory thoracic surgery in cases which are medically treatable or non-resectable. Copyright (C) 1999 Elsevier Science Ireland Ltd.

AB - Objective: to determine the contribution of percutaneous core cutting needle biopsy (PCNB) in the diagnosis of mediastinal tumors. Design: retrospective review of 70 patients with mediastinal lesions who underwent CT-guided PCNB between 1988 and 1996. Results: PCNB provided adequate material in 62/70 cases, giving a total sample rate of 88.6%. Of these 62 patients, 57 were diagnosed correctly by PCNB whereas 5/62 were misdiagnosed as nonspecific inflammation, providing an overall sensitivity of 91.9%. PCNB established a specific histologic diagnosis in 90.3% of the patients, mainly in cases of lymphoma, bronchogenic carcinoma, and thymoma. Pneumothorax was the most commonly encountered complication (11%). Hemoptysis (30-50ml) occurred in only one (1.6%) of the patients. Conclusion: CT guided PCNB is an easy and safe procedure which can provide a precise diagnosis in the majority of mediastinal tumors and can obviate the need for exploratory thoracic surgery in cases which are medically treatable or non-resectable. Copyright (C) 1999 Elsevier Science Ireland Ltd.

KW - Mediastinal lesions

KW - Percutaneous cutting needle biopsy

KW - Pneumothorax

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Percutaneous core needle biopsy in the diagnosis of mediastinal tumors

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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