@inproceedings{5cdb72937aaa4fc5b004075f787eb18c,
title = "Periodic concentration-polarization based formation of biomolecule preconcentration",
abstract = "Ionic concentration-polarization (CP)-based biomolecule preconcentration is an established method for enhancing the detection sensitivity of target biomolecules immunoassay. However, the formed preconcentrated plug of biomolecules sweeps over the surface immobilized antibodies and results in a short duration of overlap and with this also a smaller binding between target analyte and immobilized molecular probes. To overcome this, we have periodically formed a preconcentrated plug of biomolecules sweeping over the desired region of binding. We found that there is an optimal sweeping condition which results in maximum retention time of the preconcentrated plug over a desired sensing region and enhanced detection sensitivity.",
keywords = "Human IgG, Ion concentration polarization (CP), Preconcentration, Sandwich immunoassay",
author = "Sinwook Park and Ramadan Abu-Rjal and Keren Buchnik and Yechezkel Kashi and Gilad Yossifon",
note = "Publisher Copyright: {\textcopyright} 2020 CBMS-0001; 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 ; Conference date: 04-10-2020 Through 09-10-2020",
year = "2020",
month = jan,
day = "1",
language = "English",
series = "MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
publisher = "Chemical and Biological Microsystems Society",
pages = "66--67",
booktitle = "MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences",
}