Periodical multiphasic screening and lung cancer prevention

R. S. Carel

    Research output: Contribution to journalArticlepeer-review

    Abstract

    The purpose of this work is to evaluate the utilization of information gathered by multiphasic screening with respect to lung cancer detection and smoking cessation techniques. A cohort (follow-up) study is reported in which cancer incidence and factors affecting its occurrence are evaluated in a group of about 20,000 presumably healthy adults along a period of approximately 10 years following comprehensive multiphasic health examinations. Lung cancer occurrence is primarily related to smoking. The risk is higher in smokers and is dose-dependent; OR = 0.21, (CI = 0.08,.53) in never smokers, OR = 1.53 (CI = 0.8,3.2) in past and current moderate smokers, OR = 4.92 (CI = 2.18,11.11) in current heavy smokers. Moreover, smokers with compromised pulmonary function (FEVI/FVC < 75%) are at an even higher risk of developing lung cancer OR = 4.22 (CI = 2.2, 8.2) for past and current moderate smokers; and OR = 10.7 (CI-2.5, 38.6) in current heavy smokers. Information gathered in periodical multiphasic health examinations could be utilized by health professionals to encourage smoking cessation and smoking prevention in the appropriate screenees. Various elements of the multiphasic test results could contribute to such prevention efforts. While every smoker should receive appropriate evaluation and consultation regarding nicotine dependence, smokers with reduced pulmonary function represent an extra high risk group to which special attention should be given.

    Original languageEnglish
    Pages (from-to)182-187
    Number of pages6
    JournalMethods of Information in Medicine
    Volume37
    Issue number2
    DOIs
    StatePublished - 1 Jan 1998

    Keywords

    • Logistic Regression
    • Lung Cancer
    • Multiphasic Screening
    • Smoking

    ASJC Scopus subject areas

    • Health Informatics
    • Advanced and Specialized Nursing
    • Health Information Management

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