Peripheral blood T and B lymphocyte subpopulations in bell's palsy

Aharon Aviel, Ervin Ostfeld, Gabriel Marshak, Rimona Burstein, Zvi Bentwich

Research output: Contribution to journalArticlepeer-review

56 Scopus citations

Abstract

A prospective clinical, virological and immunological study was performed on 25 consecutive Bell's palsy (BP) patients. Multiple cranial nerve involvement was found in 15 patients. A significant decrease in the peripheral blood T lymphocyte percentage as well as an increase in B lymphocyte percentage (p<0.001) were found in 13 of the BP patients during the first 24 days from the clinical onset of the paralysis. No correlation was found between the peripheral blood lymphocyte subpopulations and the patient's age, sex, degree of paralysis or recovery rate. No changes were detected in the levels of immunoglobulins (IgG, IgM), complement (C3, C4) and antiviral antibodies to herpes simplex and zoster, EBV, cytomegalic virus, adenovirus, influenza and mumps. The clinical and immunological data of BP show a similar pattern to those of Guillain-Barre syndrome suggesting that BP may be an antoimmune demyelinating cranial polyneuritis which may be caused by a preceding viral infection.

Original languageEnglish
Pages (from-to)187-191
Number of pages5
JournalAnnals of Otology, Rhinology and Laryngology
Volume92
Issue number2
DOIs
StatePublished - 1 Jan 1983
Externally publishedYes

ASJC Scopus subject areas

  • Otorhinolaryngology

Fingerprint

Dive into the research topics of 'Peripheral blood T and B lymphocyte subpopulations in bell's palsy'. Together they form a unique fingerprint.

Cite this