TY - JOUR
T1 - Person-to-person transmission of Kingella kingae among day care center attendees
AU - Slonim, Ariela
AU - Walker, Elaine S.
AU - Mishori, Esther
AU - Porat, Nurith
AU - Dagan, Ron
AU - Yagupsky, Pablo
PY - 1998/12/18
Y1 - 1998/12/18
N2 - Fifty Kingella kingae organisms, isolated from tonsillar cultures of day care center attendees during an 11-month period, and 60 isolates derived from epidemiologically unrelated individuals, including 19 isolates from respiratory carriers and 41 isolates from patients with invasive infections, were typed by immunoblotting, pulsed-field gel electrophoresis, and ribotyping. One strain, defined by unique immunoblotting, pulsed-field gel electrophoresis, and ribotyping patterns, represented 14 day care isolates (28%) and was frequently isolated during the first half of the follow-up period; a second strain represented 23 (46%) isolates and prevailed during the last 5 months. Children frequently carried the same strain continuously or intermittently for weeks or months, when it was replaced by a new strain. Epidemiologically unrelated organisms showed greater variability, and no strain represented >5% of isolates. The present results support person-to- person transmission of K. kingae among young children in the day care setting.
AB - Fifty Kingella kingae organisms, isolated from tonsillar cultures of day care center attendees during an 11-month period, and 60 isolates derived from epidemiologically unrelated individuals, including 19 isolates from respiratory carriers and 41 isolates from patients with invasive infections, were typed by immunoblotting, pulsed-field gel electrophoresis, and ribotyping. One strain, defined by unique immunoblotting, pulsed-field gel electrophoresis, and ribotyping patterns, represented 14 day care isolates (28%) and was frequently isolated during the first half of the follow-up period; a second strain represented 23 (46%) isolates and prevailed during the last 5 months. Children frequently carried the same strain continuously or intermittently for weeks or months, when it was replaced by a new strain. Epidemiologically unrelated organisms showed greater variability, and no strain represented >5% of isolates. The present results support person-to- person transmission of K. kingae among young children in the day care setting.
UR - http://www.scopus.com/inward/record.url?scp=0031766134&partnerID=8YFLogxK
U2 - 10.1086/314488
DO - 10.1086/314488
M3 - Article
C2 - 9815248
AN - SCOPUS:0031766134
SN - 0022-1899
VL - 178
SP - 1843
EP - 1846
JO - Journal of Infectious Diseases
JF - Journal of Infectious Diseases
IS - 6
ER -