Phase Transition Biopolymers and Methods of Use

Ashutosh Chilkoti (Inventor), Felipe Garcia Quiroz (Inventor), Miriam Amiram (Inventor)

Research output: Patent


The present disclosure describes environmentally responsive polypeptides capable of displaying stimuli-triggered conformational changes in a reversible or irreversible manner that may be accompanied by aggregation. Polypeptides include a number of repeated motifs and may be elastomeric or non-elastomeric. The polypeptides may be used to deliver therapeutics to a biological site and to develop bioactive polypeptides that are environmentally responsive.
Original languageEnglish GB
Patent numberUS20130281624A1
StatePublished - 1 Jun 2013


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