TY - JOUR
T1 - Photochemical reactions of cannabidiol. Cyclization to Δ1-tetrahydrocannabinol and other trans formations
AU - Shani, A.
AU - Mechoulam, R.
N1 - Funding Information:
Acknowledgemenrs-We thank the U.S. NationalI nstituteo f MentalH ealthf or grants upport( grantU H-131 80)a nd the Bat-Shevad e Rotschild Fund for a junior-scientisat wardt o A.S. We areg ratefult o H. Ederya ndY . Grunfeldo f theI sraelI nstitutefo r BiologicalR esearchN. essZ iona.f or them onkeyt e.% and to Miss I. Ramatif or technicaal ssistance.
PY - 1971/1/1
Y1 - 1971/1/1
N2 - Irradiation of cannabidiol (I) in methanol gave mainly 1-methoxy-dihydrocannabidiol (II, both isomers). Irradiation of I in cyclohexane gave a complicated mixture from which, in addition to starting material, the following compounds were isolated: Δ1 tetrahydrocannabinol (III), Δ8 iso-tetrahydrocannabinol (IV), 8,9-dihydrocannabidiol (V), and 3′-cyclohexylcannabidiol (VI).
AB - Irradiation of cannabidiol (I) in methanol gave mainly 1-methoxy-dihydrocannabidiol (II, both isomers). Irradiation of I in cyclohexane gave a complicated mixture from which, in addition to starting material, the following compounds were isolated: Δ1 tetrahydrocannabinol (III), Δ8 iso-tetrahydrocannabinol (IV), 8,9-dihydrocannabidiol (V), and 3′-cyclohexylcannabidiol (VI).
UR - http://www.scopus.com/inward/record.url?scp=0000953496&partnerID=8YFLogxK
U2 - 10.1016/S0040-4020(01)90728-8
DO - 10.1016/S0040-4020(01)90728-8
M3 - Article
AN - SCOPUS:0000953496
SN - 0040-4020
VL - 27
SP - 601
EP - 606
JO - Tetrahedron
JF - Tetrahedron
IS - 3
ER -