Plasma cyclic AMP and cyclic GMP in childhood-onset psychoses

Meir Goldberg; Jocelyn Hattab; Daniel Meir; R. P. Ebstein; R. H. Belmaker

doi:10.1007/BF02409658

Plasma cyclic AMP and cyclic GMP in childhood-onset psychoses

Meir Goldberg, Jocelyn Hattab, Daniel Meir, R. P. Ebstein, R. H. Belmaker

Research output: Contribution to journal › Article › peer-review

7 Scopus citations

Abstract

Plasma cyclic AMP is a "second messenger" that may reflect levels of activity of important neurotransmitter receptors. Plasma cyclic AMP was measured in 18 patients with childhood autism, 7 patients with pervasive developmental disorder, and 12 age- and sex-matched healthy controls. Plasma cyclic AMP was significantly elevated by over 100% in both groups of patients with childhood-onset psychoses compared with controls. Plasma cyclic GMP, a nucleotide linked to different receptors, was not elevated, suggesting that the finding may be specific.

Original language	English
Pages (from-to)	159-164
Number of pages	6
Journal	Journal of Autism and Developmental Disorders
Volume	14
Issue number	2
DOIs	https://doi.org/10.1007/BF02409658
State	Published - 1 Jun 1984
Externally published	Yes

ASJC Scopus subject areas

Developmental and Educational Psychology

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10.1007/BF02409658

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title = "Plasma cyclic AMP and cyclic GMP in childhood-onset psychoses",

abstract = "Plasma cyclic AMP is a {"}second messenger{"} that may reflect levels of activity of important neurotransmitter receptors. Plasma cyclic AMP was measured in 18 patients with childhood autism, 7 patients with pervasive developmental disorder, and 12 age- and sex-matched healthy controls. Plasma cyclic AMP was significantly elevated by over 100% in both groups of patients with childhood-onset psychoses compared with controls. Plasma cyclic GMP, a nucleotide linked to different receptors, was not elevated, suggesting that the finding may be specific.",

author = "Meir Goldberg and Jocelyn Hattab and Daniel Meir and Ebstein, {R. P.} and Belmaker, {R. H.}",

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AU - Goldberg, Meir

AU - Hattab, Jocelyn

AU - Meir, Daniel

AU - Ebstein, R. P.

AU - Belmaker, R. H.

PY - 1984/6/1

Y1 - 1984/6/1

N2 - Plasma cyclic AMP is a "second messenger" that may reflect levels of activity of important neurotransmitter receptors. Plasma cyclic AMP was measured in 18 patients with childhood autism, 7 patients with pervasive developmental disorder, and 12 age- and sex-matched healthy controls. Plasma cyclic AMP was significantly elevated by over 100% in both groups of patients with childhood-onset psychoses compared with controls. Plasma cyclic GMP, a nucleotide linked to different receptors, was not elevated, suggesting that the finding may be specific.

AB - Plasma cyclic AMP is a "second messenger" that may reflect levels of activity of important neurotransmitter receptors. Plasma cyclic AMP was measured in 18 patients with childhood autism, 7 patients with pervasive developmental disorder, and 12 age- and sex-matched healthy controls. Plasma cyclic AMP was significantly elevated by over 100% in both groups of patients with childhood-onset psychoses compared with controls. Plasma cyclic GMP, a nucleotide linked to different receptors, was not elevated, suggesting that the finding may be specific.

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Plasma cyclic AMP and cyclic GMP in childhood-onset psychoses

Abstract

ASJC Scopus subject areas

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