Plasma inositol levels in lithium‐treated manic‐depressives, schizophrenics and controls

Galila Agam, Nadav Belfair, Joseph Shapiro, Hady Shimon, R. H. Belmaker

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Plasma inositol levels of lithium‐treated manic‐depressives (LTMD), schizophrenics and healthy volunteers have been studied. In contrast with the findings of Allison and Stewart, that Li treatment raises rat plasma inositol while lowering brain inositol, but in agreement with a previous report of our group of no effect of lithium on CSF inositol levels, we now show no significant difference in plasma inositol concentrations of LTMD as compared with those of control subjects. Plasma inositol levels of the schizophrenics in the present study are slightly but significantly decreased from those of controls.

Original languageEnglish
Pages (from-to)311-314
Number of pages4
JournalHuman Psychopharmacology
Issue number4
StatePublished - 1 Jan 1995


  • inositol
  • lithium
  • manic‐depressives
  • plasma
  • schizophrenics

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Psychiatry and Mental health
  • Pharmacology (medical)


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