PLGA-based nanoparticles as regenerative medicine

Deepika Sharma; Smruti Rekha Rout; Gowtham Kenguva; Mahender Khatravath; Gaurav K. Jain; Geeta Aggarwal; Prashant Kesharwani; Rambabu Dandela

doi:10.1016/B978-0-323-91215-0.00011-X

PLGA-based nanoparticles as regenerative medicine

Deepika Sharma, Smruti Rekha Rout, Gowtham Kenguva, Mahender Khatravath, Gaurav K. Jain, Geeta Aggarwal, Prashant Kesharwani, Rambabu Dandela

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

3 Scopus citations

Abstract

Nanoparticles (NPs) are spherically-shaped solids with an average 100nm size, synthesized from naturally or synthetically occurring polymers. Nowadays, nanotechnology is being widely used in biomedical science for treating a number of diseases like cancer. Poly(lactic-co-glycolic acid) (PLGA) is a successful biodegradable polymer due to its hydrolytic property, and has been approved by the FDA and EMA. PLGA NPs are incorporated in cells via fluid phase pinocytosis as well as via clathrin-mediated endocytosis. Over the past 2 decades, regenerative medicine has been studied widely due to its ability to repair or replace cells and tissues that have been impacted by age, illness, or injuries, and also to normalize congenital abnormalities. This chapter discusses the use of PLGA-based nanoparticles in regenerative medicine.

Original language	English
Title of host publication	Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery
Publisher	Elsevier
Pages	335-356
Number of pages	22
ISBN (Electronic)	9780323912150
ISBN (Print)	9780323914314
DOIs	https://doi.org/10.1016/B978-0-323-91215-0.00011-X
State	Published - 1 Jan 2023
Externally published	Yes

Keywords

CeO
Chrysin
Drug delivery
Nanomedicine
Nanoparticles
PLGA
PLGA-PEG
Polymer
Regenerative medicines

ASJC Scopus subject areas

General Engineering
General Materials Science

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/B978-0-323-91215-0.00011-X

Cite this

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title = "PLGA-based nanoparticles as regenerative medicine",

abstract = "Nanoparticles (NPs) are spherically-shaped solids with an average 100nm size, synthesized from naturally or synthetically occurring polymers. Nowadays, nanotechnology is being widely used in biomedical science for treating a number of diseases like cancer. Poly(lactic-co-glycolic acid) (PLGA) is a successful biodegradable polymer due to its hydrolytic property, and has been approved by the FDA and EMA. PLGA NPs are incorporated in cells via fluid phase pinocytosis as well as via clathrin-mediated endocytosis. Over the past 2 decades, regenerative medicine has been studied widely due to its ability to repair or replace cells and tissues that have been impacted by age, illness, or injuries, and also to normalize congenital abnormalities. This chapter discusses the use of PLGA-based nanoparticles in regenerative medicine.",

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AU - Sharma, Deepika

AU - Rout, Smruti Rekha

AU - Kenguva, Gowtham

AU - Khatravath, Mahender

AU - Jain, Gaurav K.

AU - Aggarwal, Geeta

AU - Kesharwani, Prashant

AU - Dandela, Rambabu

PY - 2023/1/1

Y1 - 2023/1/1

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KW - CeO

KW - Chrysin

KW - Drug delivery

KW - Nanomedicine

KW - Nanoparticles

KW - PLGA

KW - PLGA-PEG

KW - Polymer

KW - Regenerative medicines

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M3 - Chapter

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SN - 9780323914314

SP - 335

EP - 356

BT - Poly(lactic-co-glycolic acid) (PLGA) Nanoparticles for Drug Delivery

PB - Elsevier

ER -

PLGA-based nanoparticles as regenerative medicine

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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