Abstract
Pediatric vaccination against invasive pneumococcal disease (IPD) made a breakthrough in 2000 when a 7-valent pneumococcal conjugate vaccine was licensed. Subsequently, the spectrum was to introduce 10- and 13-valent conjugate vaccines PCV10 and PCV 13, which cover most of the IPD serotypes in children in developed countries. Those vaccines are highly effective against IPD caused by the vaccine serotypes, and are now part of infant immunization programs in most European countries and elsewhere. While effective against IPD, the conjugate vaccines have much less efficacy against pneumococcal pneumonia which remains a major cause of childhood mortality globally.
Original language | English |
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Title of host publication | Pediatric Vaccines and Vaccinations |
Subtitle of host publication | A European Textbook: Second Edition |
Publisher | Springer International Publishing |
Pages | 223-247 |
Number of pages | 25 |
ISBN (Electronic) | 9783030771737 |
ISBN (Print) | 9783030771720 |
DOIs | |
State | Published - 1 Jan 2021 |
ASJC Scopus subject areas
- General Medicine
- General Immunology and Microbiology
- General Pharmacology, Toxicology and Pharmaceutics