PO-0961: DNA damage and repair influence tumor sensitivity to diffusing alpha emitters radiation therapy

Y Keisari; R Etzyoni; H Bittan; E Lazarov; M Efrati; M Schmidt; T Cooks; L Arazi; I Kelson

doi:10.1016/S0167-8140(17)32301-0

PO-0961: DNA damage and repair influence tumor sensitivity to diffusing alpha emitters radiation therapy

Y Keisari, R Etzyoni, H Bittan, E Lazarov, M Efrati, M Schmidt, T Cooks, L Arazi, I Kelson

Research output: Contribution to journal › Short survey › peer-review

Abstract

We developed an alpha radiation based brachytherapy, which provides efficient ablation of solid tumors by alpha radiation. This treatment termed, Diffusing Alpha
emitters Radiation Therapy (DaRT) utilizes radium-224 loaded wires, which when inserted into the tumor release by recoil short-lived alpha-emitting atoms. These atoms disperse in the tumor, and spray it with highly destructive
alpha radiation.

Original language	English
Pages (from-to)	S531
Number of pages	1
Journal	Radiotherapy and Oncology
Volume	123
Issue number	supplement 1
DOIs	https://doi.org/10.1016/S0167-8140(17)32301-0
State	Published - May 2017

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title = "PO-0961: DNA damage and repair influence tumor sensitivity to diffusing alpha emitters radiation therapy",

abstract = "We developed an alpha radiation based brachytherapy, which provides efficient ablation of solid tumors by alpha radiation. This treatment termed, Diffusing Alphaemitters Radiation Therapy (DaRT) utilizes radium-224 loaded wires, which when inserted into the tumor release by recoil short-lived alpha-emitting atoms. These atoms disperse in the tumor, and spray it with highly destructivealpha radiation. ",

author = "Y Keisari and R Etzyoni and H Bittan and E Lazarov and M Efrati and M Schmidt and T Cooks and L Arazi and I Kelson",

year = "2017",

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language = "English",

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T2 - DNA damage and repair influence tumor sensitivity to diffusing alpha emitters radiation therapy

AU - Keisari, Y

AU - Etzyoni, R

AU - Bittan, H

AU - Lazarov, E

AU - Efrati, M

AU - Schmidt, M

AU - Cooks, T

AU - Arazi, L

AU - Kelson, I

PY - 2017/5

Y1 - 2017/5

N2 - We developed an alpha radiation based brachytherapy, which provides efficient ablation of solid tumors by alpha radiation. This treatment termed, Diffusing Alphaemitters Radiation Therapy (DaRT) utilizes radium-224 loaded wires, which when inserted into the tumor release by recoil short-lived alpha-emitting atoms. These atoms disperse in the tumor, and spray it with highly destructivealpha radiation.

AB - We developed an alpha radiation based brachytherapy, which provides efficient ablation of solid tumors by alpha radiation. This treatment termed, Diffusing Alphaemitters Radiation Therapy (DaRT) utilizes radium-224 loaded wires, which when inserted into the tumor release by recoil short-lived alpha-emitting atoms. These atoms disperse in the tumor, and spray it with highly destructivealpha radiation.

U2 - 10.1016/S0167-8140(17)32301-0

DO - 10.1016/S0167-8140(17)32301-0

M3 - Short survey

SN - 0167-8140

VL - 123

SP - S531

JO - Radiotherapy and Oncology

JF - Radiotherapy and Oncology

IS - supplement 1

ER -

PO-0961: DNA damage and repair influence tumor sensitivity to diffusing alpha emitters radiation therapy

Abstract

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