Polyagglutination in Hospitalized Patients: A Prospective Study

D. Buskila, C. Levene, G. W.G. Bird, N. A. Levene

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Abstract. A hospital population at high risk for red cell polyagglutination was studied prospectively in search for cryptantigen exposure. The patients included in this study suffered from: malignancies, sepsis, direct antiglobulin test (DAT) negative anemias and various combinations of these three. 238 patients were examined, and 18 of these (7.6%) were found to have exposed cryptantigens on their erythrocytes. This is an unexpectedly high percentage. Our findings suggest that cryptantigen exposure on the red cells is a more common phenomenon than previously described, especially when looked for in a carefully chosen population. The red cells of these patients are potentially polyagglutinable, and screening with lectins will ensure their pretransfusion identification and evaluation.

Original languageEnglish
Pages (from-to)99-102
Number of pages4
JournalVox Sanguinis
Volume52
Issue number1-2
DOIs
StatePublished - 1 Jan 1987
Externally publishedYes

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