Polycystic ovary syndrome: A single gene mutation or an evolving set of symptoms

Zion Ben-Rafael, Raoul Orvieto

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


Polycystic ovary syndrome is one of the most common endocrinopathies among women. Nevertheless, there is no one single acceptable definition for this syndrome, its pathophysiology is not completely understood and its etiology remains an enigma. Several studies have examined the genetic basis of polycystic ovary syndrome with varying results, probably caused by the different criteria used to define the syndrome. These studies, together with studies that deal with reclassification of polycystic ovary syndrome, are described in the following review. Furthermore, a simplified alternative approach to this symptom complex is proposed.

Original languageEnglish
Pages (from-to)169-173
Number of pages5
JournalCurrent Opinion in Obstetrics and Gynecology
Issue number3
StatePublished - 1 Dec 2000
Externally publishedYes

ASJC Scopus subject areas

  • Obstetrics and Gynecology


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