Polysaccharide production by plant cells in suspension: Experiments and mathematical modeling

R. Glicklis, D. Mills, D. Sitton, W. Stortelder, J. C. Merchuk

Research output: Contribution to journalArticlepeer-review

18 Scopus citations


Symphytum officinale L cells were grown in Erlenmeyer flasks at four different temperatures: 15, 20, 25, and 30°C. A mathematical model of the culture growth is presented. The intracellular and extracellular products are considered in separate equations. An interrelation between fresh weight, dry weight, and viability is considered in the balances. The model includes a description of the changes in time of wet and dry biomass, cell viability, substrate concentration and polysaccharide concentration, both intra- and extracellular. The model was tested by fitting the numerical results to the data obtained.

Original languageEnglish
Pages (from-to)732-740
Number of pages9
JournalBiotechnology and Bioengineering
Issue number6
StatePublished - 20 Mar 1998


  • Mathematical model
  • Plant cell suspension
  • Polysaccharide

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering
  • Applied Microbiology and Biotechnology


Dive into the research topics of 'Polysaccharide production by plant cells in suspension: Experiments and mathematical modeling'. Together they form a unique fingerprint.

Cite this