@article{2086a440caa14902a9c683983eadebb9,
title = "Post-transcriptional regulation of gene expression in trypanosomes and leishmanias",
abstract = "Gene expression in Kinetoplastids is very unusual in that the open reading frames are arranged in long polycistronic arrays, monocistronic mRNAs being created by post-transcriptional processing. Thus the regulation of gene expression is post-transcriptional. We here discuss recent results concerning the enzymes required for mRNA degradation, and components of the translation initiation machinery, and how both are regulated.",
keywords = "Degradation, Leishmania, Translation, Trypanosoma, mRNA",
author = "Christine Clayton and Michal Shapira",
note = "Funding Information: We thank Mark Carrington (University of Cambridge, England) and Kirill Alexandrov from the Max-Planck-Institute for Molecular Physiology, Dortmund (Germany), for communicating unpublished results. Work on RNA in CC's laboratory is supported by the Deutsche Forschungsgemeinschaft and the Wellcome trust, and a joint grant with MS from the German-Israeli Foundation (GIF). Work in MS's laboratory is also supported by the UNICEF/UNDP/World Bank/WHO Special Programme for Research and Training in Tropical Diseases (TDR) and by the Israel Ministry of Health. ",
year = "2007",
month = dec,
day = "1",
doi = "10.1016/j.molbiopara.2007.07.007",
language = "English",
volume = "156",
pages = "93--101",
journal = "Molecular and Biochemical Parasitology",
issn = "0166-6851",
publisher = "Elsevier",
number = "2",
}