Postchemotherapy Histiocyte-Rich Pseudotumor of the Spleen Simulating Residual Disease in a Patient with Non-Hodgkin Lymphoma on FDG PET/CT

Nir Hod; Sophie Lantsberg; Reut Anconina; Daniel Levin; Karen Nalbandyan; Itai Levi

doi:10.1097/RLU.0000000000002568

Postchemotherapy Histiocyte-Rich Pseudotumor of the Spleen Simulating Residual Disease in a Patient with Non-Hodgkin Lymphoma on FDG PET/CT

Nir Hod, Sophie Lantsberg, Reut Anconina, Daniel Levin, Karen Nalbandyan, Itai Levi

Medical School for International Health

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

A 64-year-old man was treated with multiagent chemotherapy owing to high-grade non-Hodgkin lymphoma presenting as a bulky disease involving the spleen. Interim and posttreatment sequential FDG PET/CT scans revealed a residual splenic mass showing markedly intense FDG uptake suspected of a residual viable lymphoma. To definitely decide about the appropriate treatment, a laparoscopic splenectomy was performed. Histopathologic specimen was compatible with the rare diagnosis of postchemotherapy histiocyte-rich pseudotumor of the spleen, a potential pitfall simulating viable disease on FDG PET/CT.

Original language	English
Pages (from-to)	E409-E412
Journal	Clinical Nuclear Medicine
Volume	44
Issue number	6
DOIs	https://doi.org/10.1097/RLU.0000000000002568
State	Published - 1 Jun 2019

Keywords

FDG PET/CT
follicular lymphoma
non-Hodgkin lymphoma
pitfall
postchemotherapy histiocyte-rich pseudotumor
spleen

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/RLU.0000000000002568

Cite this

@article{928fd0e895324430a6324739885254d3,

title = "Postchemotherapy Histiocyte-Rich Pseudotumor of the Spleen Simulating Residual Disease in a Patient with Non-Hodgkin Lymphoma on FDG PET/CT",

abstract = "A 64-year-old man was treated with multiagent chemotherapy owing to high-grade non-Hodgkin lymphoma presenting as a bulky disease involving the spleen. Interim and posttreatment sequential FDG PET/CT scans revealed a residual splenic mass showing markedly intense FDG uptake suspected of a residual viable lymphoma. To definitely decide about the appropriate treatment, a laparoscopic splenectomy was performed. Histopathologic specimen was compatible with the rare diagnosis of postchemotherapy histiocyte-rich pseudotumor of the spleen, a potential pitfall simulating viable disease on FDG PET/CT.",

keywords = "FDG PET/CT, follicular lymphoma, non-Hodgkin lymphoma, pitfall, postchemotherapy histiocyte-rich pseudotumor, spleen",

author = "Nir Hod and Sophie Lantsberg and Reut Anconina and Daniel Levin and Karen Nalbandyan and Itai Levi",

year = "2019",

month = jun,

day = "1",

doi = "10.1097/RLU.0000000000002568",

language = "English",

volume = "44",

pages = "E409--E412",

journal = "Clinical Nuclear Medicine",

issn = "0363-9762",

publisher = "Lippincott Williams and Wilkins",

number = "6",

}

TY - JOUR

T1 - Postchemotherapy Histiocyte-Rich Pseudotumor of the Spleen Simulating Residual Disease in a Patient with Non-Hodgkin Lymphoma on FDG PET/CT

AU - Hod, Nir

AU - Lantsberg, Sophie

AU - Anconina, Reut

AU - Levin, Daniel

AU - Nalbandyan, Karen

AU - Levi, Itai

PY - 2019/6/1

Y1 - 2019/6/1

N2 - A 64-year-old man was treated with multiagent chemotherapy owing to high-grade non-Hodgkin lymphoma presenting as a bulky disease involving the spleen. Interim and posttreatment sequential FDG PET/CT scans revealed a residual splenic mass showing markedly intense FDG uptake suspected of a residual viable lymphoma. To definitely decide about the appropriate treatment, a laparoscopic splenectomy was performed. Histopathologic specimen was compatible with the rare diagnosis of postchemotherapy histiocyte-rich pseudotumor of the spleen, a potential pitfall simulating viable disease on FDG PET/CT.

AB - A 64-year-old man was treated with multiagent chemotherapy owing to high-grade non-Hodgkin lymphoma presenting as a bulky disease involving the spleen. Interim and posttreatment sequential FDG PET/CT scans revealed a residual splenic mass showing markedly intense FDG uptake suspected of a residual viable lymphoma. To definitely decide about the appropriate treatment, a laparoscopic splenectomy was performed. Histopathologic specimen was compatible with the rare diagnosis of postchemotherapy histiocyte-rich pseudotumor of the spleen, a potential pitfall simulating viable disease on FDG PET/CT.

KW - FDG PET/CT

KW - follicular lymphoma

KW - non-Hodgkin lymphoma

KW - pitfall

KW - postchemotherapy histiocyte-rich pseudotumor

KW - spleen

UR - https://www.scopus.com/pages/publications/85065598872

U2 - 10.1097/RLU.0000000000002568

DO - 10.1097/RLU.0000000000002568

M3 - Article

C2 - 30985428

AN - SCOPUS:85065598872

SN - 0363-9762

VL - 44

SP - E409-E412

JO - Clinical Nuclear Medicine

JF - Clinical Nuclear Medicine

IS - 6

ER -

Postchemotherapy Histiocyte-Rich Pseudotumor of the Spleen Simulating Residual Disease in a Patient with Non-Hodgkin Lymphoma on FDG PET/CT

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this