Total elimination of soluble boron control from PWRs appears to offer significant advantages in safety, reactor operation, capital equipment savings, and uranium resource utilization. Based on a minicore computational model, an optimized combination of poisons has been found which would permit practically total elimination of soluble boron control. The poisons used are gadolinium, boron, hafnium, and samarium in such combination as to match closely the boron letdown curve. Only small increases in control rod motion would be necessary for complete reactivity control. The analysis is being extended to account for realistic core configurations to determine the necessary refinements in order to ensure acceptable power distributions and to minimize burnable poison residues at core boundaries. Fuel management schemes to take advantage of the elimination of soluble boron control are also being developed.