Potential Role of Fluoroquinolone Therapy in Childhood Otitis Media

Ron Dagan, Adriano Arguedas, Urs B. Schaad

Research output: Contribution to journalReview articlepeer-review

19 Scopus citations


Increased resistance of pneumococci and other pathogens to available antibiotics raises concerns about bacteriologic and clinical failure in children with acute otitis media. Few therapeutic options exist for patients with recurrent infections or recent treatment failure. The limited experience from the compassionate use of fluoroquinolones in pediatrics and pediatric studies has not been linked unequivocally with arthrotoxicity, the primary safety concern in children. Newer 8-methoxyfluoroquinolones may have a role in selected cases associated with multidrug-resistant pathogens.

Original languageEnglish
Pages (from-to)390-398
Number of pages9
JournalPediatric Infectious Disease Journal
Issue number5
StatePublished - 1 May 2004
Externally publishedYes


  • Antimicrobial resistance
  • Fluoroquinolones
  • Gatifloxacin
  • Otitis media
  • Pediatrics

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases


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