Pre-eclampsia and future female malignancy

Asnat Walfisch; Roy Kessous; Ehud Davidson; Ruslan Sergienko; Eyal Sheiner

doi:10.3109/10641955.2015.1071838

Pre-eclampsia and future female malignancy

Asnat Walfisch
, Roy Kessous
, Ehud Davidson
, Ruslan Sergienko
, Eyal Sheiner

Research output: Contribution to journal › Article › peer-review

8 Scopus citations

Abstract

Objective: To investigate an association between pre-eclampsia and future genital tract and breast malignancies. Methods: The incidence of genital tract and breast malignancies was compared in a cohort of women with and without a history of pre-eclampsia. Cumulative incidence was assessed using a Kaplan-Meier survival curve. Results: During the study period, 103 180 deliveries met the inclusion criteria; 8.1% occurred in patients with pre-eclampsia. Patients with pre-eclampsia did not have a significantly different risk of genital tract or breast malignancies. The results remained insignificant in a sub-analysis based on malignancy type, pre-eclampsia severity and number of episodes per patient. No difference in cumulative incidence was demonstrated. Conclusion: Pre-eclampsia does not appear to influence the risk of future genital tract or breast malignancies.

Original language	English
Pages (from-to)	456-463
Number of pages	8
Journal	Hypertension in Pregnancy
Volume	34
Issue number	4
DOIs	https://doi.org/10.3109/10641955.2015.1071838
State	Published - 2 Oct 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Breast cancer
Genital malignancy
Gestational hypertension
Long-term follow up
Pregnancy

ASJC Scopus subject areas

Internal Medicine
Obstetrics and Gynecology

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10.3109/10641955.2015.1071838

Cite this

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title = "Pre-eclampsia and future female malignancy",

abstract = "Objective: To investigate an association between pre-eclampsia and future genital tract and breast malignancies. Methods: The incidence of genital tract and breast malignancies was compared in a cohort of women with and without a history of pre-eclampsia. Cumulative incidence was assessed using a Kaplan-Meier survival curve. Results: During the study period, 103 180 deliveries met the inclusion criteria; 8.1\% occurred in patients with pre-eclampsia. Patients with pre-eclampsia did not have a significantly different risk of genital tract or breast malignancies. The results remained insignificant in a sub-analysis based on malignancy type, pre-eclampsia severity and number of episodes per patient. No difference in cumulative incidence was demonstrated. Conclusion: Pre-eclampsia does not appear to influence the risk of future genital tract or breast malignancies.",

keywords = "Breast cancer, Genital malignancy, Gestational hypertension, Long-term follow up, Pregnancy",

author = "Asnat Walfisch and Roy Kessous and Ehud Davidson and Ruslan Sergienko and Eyal Sheiner",

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doi = "10.3109/10641955.2015.1071838",

language = "English",

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journal = "Hypertension in Pregnancy",

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}

TY - JOUR

T1 - Pre-eclampsia and future female malignancy

AU - Walfisch, Asnat

AU - Kessous, Roy

AU - Davidson, Ehud

AU - Sergienko, Ruslan

AU - Sheiner, Eyal

PY - 2015/10/2

Y1 - 2015/10/2

N2 - Objective: To investigate an association between pre-eclampsia and future genital tract and breast malignancies. Methods: The incidence of genital tract and breast malignancies was compared in a cohort of women with and without a history of pre-eclampsia. Cumulative incidence was assessed using a Kaplan-Meier survival curve. Results: During the study period, 103 180 deliveries met the inclusion criteria; 8.1% occurred in patients with pre-eclampsia. Patients with pre-eclampsia did not have a significantly different risk of genital tract or breast malignancies. The results remained insignificant in a sub-analysis based on malignancy type, pre-eclampsia severity and number of episodes per patient. No difference in cumulative incidence was demonstrated. Conclusion: Pre-eclampsia does not appear to influence the risk of future genital tract or breast malignancies.

AB - Objective: To investigate an association between pre-eclampsia and future genital tract and breast malignancies. Methods: The incidence of genital tract and breast malignancies was compared in a cohort of women with and without a history of pre-eclampsia. Cumulative incidence was assessed using a Kaplan-Meier survival curve. Results: During the study period, 103 180 deliveries met the inclusion criteria; 8.1% occurred in patients with pre-eclampsia. Patients with pre-eclampsia did not have a significantly different risk of genital tract or breast malignancies. The results remained insignificant in a sub-analysis based on malignancy type, pre-eclampsia severity and number of episodes per patient. No difference in cumulative incidence was demonstrated. Conclusion: Pre-eclampsia does not appear to influence the risk of future genital tract or breast malignancies.

KW - Breast cancer

KW - Genital malignancy

KW - Gestational hypertension

KW - Long-term follow up

KW - Pregnancy

UR - https://www.scopus.com/pages/publications/84951567386

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DO - 10.3109/10641955.2015.1071838

M3 - Article

AN - SCOPUS:84951567386

SN - 1064-1955

VL - 34

SP - 456

EP - 463

JO - Hypertension in Pregnancy

JF - Hypertension in Pregnancy

IS - 4

ER -

Pre-eclampsia and future female malignancy

Abstract

UN SDGs

Keywords

ASJC Scopus subject areas

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