Predicting mutant outcome by combining deep mutational scanning and machine learning

Keyphrases

• Machine Learning 100%
• Protein Variants 100%
• Deep mutational Scanning 100%
• Green Fluorescent Protein 33%
• Proteinase Inhibitor 33%
• Novel Protein 33%
• Computational Challenges 33%
• Structural Features 33%
• Statistical Model 33%
• Immunoglobulin G 33%
• Functional Outcome 33%
• Machine Learning Approach 33%
• Single-point mutation 33%
• Structural Stability 33%
• Scanned Data 33%
• Amyloid Precursor Protein 33%
• Computational Scheme 33%
• Novel Machine 33%
• Mutational Landscape 33%
• Multiple mutations 33%
• Protease Specificity 33%
• One-hot 33%
• Streptococcal Protein G 33%
• Mutational Scanning 33%
• Predictive Statistical Model 33%
• Functional mutation 33%

Biochemistry, Genetics and Molecular Biology

• Green Fluorescent Protein 100%
• Protease 100%
• Immunoglobulin G 100%
• Protein G 100%
• Amyloid Precursor Protein 100%
• Streptococcal Proteins 100%

Neuroscience

• Protein Variant 100%
• Green Fluorescent Protein 33%
• Proteinase 33%
• Protein G 33%
• Amyloid Precursor Protein 33%
• Immunoglobulin G 33%