"Predicting" polymorphs of pharmaceuticals using hydrogen bond propensities: Probenecid and its two single-crystal-to-single-crystal phase transitions

Keyphrases

• Polymorph 100%
• Hydrogen Bonds (H-bonds) 100%
• Probenecid 100%
• Single-crystal-to-single-crystal 100%
• Crystal Phase Transition 100%
• Crystal Form 50%
• Differential Scanning Calorimetry 25%
• High Probability 25%
• Polymorphism 25%
• Mercury 25%
• Appropriate Temperature 25%
• Cambridge Structural Database 25%
• Solution Crystallization 25%
• Single-crystal Structure Determination 25%
• Single-crystal-to-single-crystal Transformation 25%
• Multiple Crystals 25%
• Propensity Analysis 25%
• Database Software 25%
• Crystallization Screening 25%

Chemistry

• Single Crystalline Solid 100%
• Hydrogen Bonding 100%
• Probenecid 100%
• Crystalline Material 100%
• Crystal Morphology 50%
• Structure 25%
• Differential Scanning Calorimetry 25%
• Crystal Structure Determination 25%
• Single-Crystal-to-Single-Crystal Transformation 25%

Biochemistry, Genetics and Molecular Biology

• Hydrogen Bond 100%
• Single Crystal 100%
• Solution and Solubility 33%
• Structure Determination 33%
• Crystal Structure 33%
• Structural Database 33%
• Differential Scanning Calorimetry 33%
• Single-Crystal-to-Single-Crystal Transformation 33%