Abstract
Objective: To present our experience with management of parturients with multiple sclerosis and to examine the role of intravenous immunoglobulin (IVIg) in the prevention of postpartum exacerbations of the disease. Methods: Fifteen patients with multiple sclerosis with a relapsing-remitting course were followed during pregnancy and 6 months postpartum. To prevent postpartum exacerbations, 14 of the patients had received IVIg after delivery. Results: None of the patients who received postpartum IVIg relapsed during the 6 months after delivery. None of the observed obstetric complications nor the operative deliveries could be related to the coexistence of multiple sclerosis. Conclusion: Postpartum IVIg treatment is beneficial in preventing acute childbirth-associated exacerbations in patients with relapsing-remitting multiple sclerosis. Furthermore, this disease does not seem to increase obstetric complications. Copyright (C) 1999 Elsevier Science Ireland Ltd.
| Original language | English |
|---|---|
| Pages (from-to) | 191-194 |
| Number of pages | 4 |
| Journal | European Journal of Obstetrics and Gynecology and Reproductive Biology |
| Volume | 82 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1 Feb 1999 |
| Externally published | Yes |
Keywords
- IVIg
- Multiple sclerosis
- Post-partum exacerbations
ASJC Scopus subject areas
- Reproductive Medicine
- Obstetrics and Gynecology
