Pregnancy Course of 10 Women Diagnosed with Chronic Lymphocytic Leukemia

Tamar Tadmor, Guy Melamed, Hillel Alapi, Sivan Gazit, Tal Patalon, Lior Rokach

Research output: Contribution to journalArticlepeer-review


Pregnancies following diagnosis of chronic lymphocytic leukemia (CLL) are rare events, mainly because the disease is typically diagnosed in the elderly. Literature on the topic is based only on case reports, and limited data are available on the influence of pregnancy on CLL course. In this retrospective study, we aimed to summarize the clinical and laboratory course of 10 women with CLL who became pregnant. None of the patients had significant changes in blood count during or after pregnancy or had complications such as infection, autoimmune phenomenon, or preeclampsia. Four out of 10 pregnancies were terminated with an early miscarriage. Following labor, 1 patient started anti-CLL treatment due to preexisting anemia, but none of the women required therapy during CLL progression during the first 2 years of follow-up. We conclude that based on our serial, pregnancy does not negatively impact on CLL course.

Original languageEnglish
Pages (from-to)379-383
Number of pages5
JournalActa Haematologica
Issue number5
StatePublished - 5 Jun 2023


  • CLL
  • Chronic lymphocytic leukemia
  • Labor
  • Pregnancy

ASJC Scopus subject areas

  • Hematology


Dive into the research topics of 'Pregnancy Course of 10 Women Diagnosed with Chronic Lymphocytic Leukemia'. Together they form a unique fingerprint.

Cite this