Pregnancy outcome in women with pruritus gravidarum

Eyal Sheiner, Iris Ohel, Amalia Levy, Miriam Katz

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


OBJECTIVE: To investigate obstetric risk factors and pregnancy outcome in women with pruritus gravidarum who delivered during a 15-year period. METHODS: A population-based study comparing all pregnancies in women with and without pruritus gravidarum delivered between 1988 and 2002 was conducted. A multivariable logistic regression model was constructed in order to find independent risk factors associated with pruritus gravidarum. RESULTS: During the study period there were 159,197 deliveries, of which 376 (0.2%) occurred in patients with pruritus gravidarum. Using a multivariable analysis, the following conditions were found to be significantly associated with pruritus gravidarum: twin pregnancies, fertility treatments, diabetes mellitus and nulliparity. No significant differences were noted between the groups regarding perinatal outcomes, such as birth weight, low Apgar scores or perinatal mortality. Pruritus gravidarum was associated with higher rates of labor induction, and accordingly those fetuses were more likely to be delivered by cesarean delivery. CONCLUSION: Pruritus gravidarum, associated with multiple gestations, fertility treatments, diabetes mellitus and nulliparity, is not associated with adverse perinatal outcomes. However, there are higher rates of labor induction and cesarean delivery.

Original languageEnglish
Pages (from-to)394-398
Number of pages5
JournalThe Journal of reproductive medicine
Issue number5
StatePublished - 1 May 2006
Externally publishedYes


  • Cesarean section
  • Multiparity
  • Nulliparity
  • Pregnancy outcome
  • Pruritus gravidarum

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology


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