Pregnancy outcome in women with psoriasis

Gila Ben-David, Eyal Sheiner, Mordechai Hallak, Amalia Levy

    Research output: Contribution to journalArticlepeer-review

    67 Scopus citations

    Abstract

    OBJECTIVE: To determine pregnancy outcome in women with psoriasis. STUDY DESIGN: A case-control study of 145 deliveries in women with psoriasis during the years 1988-2004 was performed. For every birth, 6 births to nonpsoriatic women (n = 860) were randomly selected and adjusted for ethnicity and year of delivery. RESULTS: Recurrent abortions (OR = 2.1, 95% CI 1.1-4.9, p = 0.04) and chronic hypertension (OR = 2.9, 95% CI 1.01-8.3, p = 0.048) were significantly associated with psoriasis in a multivariable analysis with backward elimination. Psoriasis was also found as an independent risk factor for cesarean delivery (CD) in another multivariable analysis with CD as the outcome variable (OR = 4.1, 95% CI 2.3-7.5, p < 0.001). CONCLUSION: A significant association exists between psoriasis and pregnancy complications. Moreover, psoriasis is an independent risk factor for CD. Thus, physicians should keep in mind that psoriasis might have nondermatologic implications that may adversely affect pregnancy.

    Original languageEnglish
    Pages (from-to)183-187
    Number of pages5
    JournalJournal of Reproductive Medicine
    Volume53
    Issue number3
    StatePublished - 1 Mar 2008

    Keywords

    • Autoimmunity
    • Pregnancy outcome
    • Psoriasis

    ASJC Scopus subject areas

    • Reproductive Medicine
    • Obstetrics and Gynecology

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