Pregnancy outcome of patients with celiac disease

Rachel Pope, Eyal Sheiner

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    1 Scopus citations

    Abstract

    Celiac disease, i.e. permanent intolerance to gluten, has an autoimmune mechanism and is commonly undiagnosed. Controversy exists among the literature regarding the association between celiac and infertility, abortions, intra-uterine growth restriction (IUGR), and stillbirths. Individuals with celiac disease may be subfertile, or suffer infertility or repeat spontaneous abortions (RSA's). If pregnancy is achieved without treating the disease, there are often higher rates of IUGR, and low birthweight (LBW) compared to the general population. However, even when properly managed, adverse effects are still possible and "silent" cases of celiac disease have been found to also impose risk. Therefore, celiac disease should be considered among idiopathic infertility, RSA's, and IUGR. It should be immediately and strictly treated in order to avoid future risks, and fetal growth must be monitored throughout pregnancy. Control of a gluten-free diet is important in terms of healthy reproduction and further studies should focus on screening for celiac disease.

    Original languageEnglish
    Title of host publicationCeliac Disease
    Subtitle of host publicationEtiology, Diagnosis, and Treatment
    PublisherNova Science Publishers, Inc.
    Pages227-236
    Number of pages10
    ISBN (Print)9781606926338
    StatePublished - 1 Mar 2009

    Keywords

    • Celiac disease
    • Fertility.
    • Intrauterine growth restriction
    • Pregnancy

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