Premedication with metoclopramide decreases the frequency of methohexital induced hiccup

Anatoli Stav; Natan Weksler; Michael Berman; Lusia Lemberg; Leonid Ribak; Anat Segal; Evgenia Machamid; Leon Ovadia; Ahud Sternberg

doi:10.1007/s0054020060017

Premedication with metoclopramide decreases the frequency of methohexital induced hiccup

Anatoli Stav, Natan Weksler, Michael Berman, Lusia Lemberg, Leonid Ribak, Anat Segal, Evgenia Machamid, Leon Ovadia, Ahud Sternberg

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Metoclopramide is one of many drugs that have been recommended for the treatment of intractable hiccup. Methohexital may produce hiccup during induction of general anesthesia. 211 women received methohexital for induction and maintenance of general anesthesia for short gynaecological procedures. All the patients were premedicated with fentanyl, diazepam and atropine. 109 patients were randomly selected to receive metoclopramide before induction of anesthesia; the remaining 102 patients served as a control group, and were anesthetized without metoclopramide premedication. The frequency of hiccup was compared between the two groups. 7 patients had hiccup in the metoclopramide premedicated group, as compared to 17 patients in the control group. This difference was statistically significant. We conclude that metoclopramide reduces the frequency of methohexital induced hiccup, and recommend that metoclopramide be routinely used for the premedication of methohexital injection. Stav A, Weksler N, Berman M: premedication with metcoclopramide decreases the frequency of methohexital induced hiccup. J Anesth 6: 17–20, 1992

Original language	English
Pages (from-to)	17-20
Number of pages	4
Journal	Journal of Anesthesia
Volume	6
Issue number	1
DOIs	https://doi.org/10.1007/s0054020060017
State	Published - 1 Jan 1992
Externally published	Yes

Keywords

Hiccup
Methohexital
Metoclopramide

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1007/s0054020060017

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title = "Premedication with metoclopramide decreases the frequency of methohexital induced hiccup",

abstract = "Metoclopramide is one of many drugs that have been recommended for the treatment of intractable hiccup. Methohexital may produce hiccup during induction of general anesthesia. 211 women received methohexital for induction and maintenance of general anesthesia for short gynaecological procedures. All the patients were premedicated with fentanyl, diazepam and atropine. 109 patients were randomly selected to receive metoclopramide before induction of anesthesia; the remaining 102 patients served as a control group, and were anesthetized without metoclopramide premedication. The frequency of hiccup was compared between the two groups. 7 patients had hiccup in the metoclopramide premedicated group, as compared to 17 patients in the control group. This difference was statistically significant. We conclude that metoclopramide reduces the frequency of methohexital induced hiccup, and recommend that metoclopramide be routinely used for the premedication of methohexital injection. Stav A, Weksler N, Berman M: premedication with metcoclopramide decreases the frequency of methohexital induced hiccup. J Anesth 6: 17–20, 1992",

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author = "Anatoli Stav and Natan Weksler and Michael Berman and Lusia Lemberg and Leonid Ribak and Anat Segal and Evgenia Machamid and Leon Ovadia and Ahud Sternberg",

year = "1992",

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doi = "10.1007/s0054020060017",

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T1 - Premedication with metoclopramide decreases the frequency of methohexital induced hiccup

AU - Stav, Anatoli

AU - Weksler, Natan

AU - Berman, Michael

AU - Lemberg, Lusia

AU - Ribak, Leonid

AU - Segal, Anat

AU - Machamid, Evgenia

AU - Ovadia, Leon

AU - Sternberg, Ahud

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Metoclopramide is one of many drugs that have been recommended for the treatment of intractable hiccup. Methohexital may produce hiccup during induction of general anesthesia. 211 women received methohexital for induction and maintenance of general anesthesia for short gynaecological procedures. All the patients were premedicated with fentanyl, diazepam and atropine. 109 patients were randomly selected to receive metoclopramide before induction of anesthesia; the remaining 102 patients served as a control group, and were anesthetized without metoclopramide premedication. The frequency of hiccup was compared between the two groups. 7 patients had hiccup in the metoclopramide premedicated group, as compared to 17 patients in the control group. This difference was statistically significant. We conclude that metoclopramide reduces the frequency of methohexital induced hiccup, and recommend that metoclopramide be routinely used for the premedication of methohexital injection. Stav A, Weksler N, Berman M: premedication with metcoclopramide decreases the frequency of methohexital induced hiccup. J Anesth 6: 17–20, 1992

AB - Metoclopramide is one of many drugs that have been recommended for the treatment of intractable hiccup. Methohexital may produce hiccup during induction of general anesthesia. 211 women received methohexital for induction and maintenance of general anesthesia for short gynaecological procedures. All the patients were premedicated with fentanyl, diazepam and atropine. 109 patients were randomly selected to receive metoclopramide before induction of anesthesia; the remaining 102 patients served as a control group, and were anesthetized without metoclopramide premedication. The frequency of hiccup was compared between the two groups. 7 patients had hiccup in the metoclopramide premedicated group, as compared to 17 patients in the control group. This difference was statistically significant. We conclude that metoclopramide reduces the frequency of methohexital induced hiccup, and recommend that metoclopramide be routinely used for the premedication of methohexital injection. Stav A, Weksler N, Berman M: premedication with metcoclopramide decreases the frequency of methohexital induced hiccup. J Anesth 6: 17–20, 1992

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Premedication with metoclopramide decreases the frequency of methohexital induced hiccup

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Keywords

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