Preterm deliveries among women with MacDonald cerclage performed due to cervical incompetence

Eyal Sheiner, Asher Bashiri, Ilana Shoham-Vardi, Reli Hershkovitz, Moshe Mazor

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Objective: The study was aimed to assess the impact of obstetric risk factors for preterm delivery among women with MacDonald cerclage performed due to cervical incompetence. Study Design: A cohort study was conducted including all patients with MacDonald cerclage performed at 12-14 weeks gestation due to cervical incompetence (n = 793). Deliveries occurred between the years 1988 and 2002 in a University Medical Center. A multiple linear regression model was used to assess the impact of maternal characteristics as well as pregnancy complications on the length of pregnancy. Results: The following factors were found to be associated with preterm delivery among these patients, in the univariate analysis: nulliparity, fertility treatments, severe preeclampsia, second-trimester bleeding, premature rupture of membranes (PROM), chorioamnionitis and placental abruption. Using a multiple linear regression model, with backward elimination, the impact of these variables on the length of pregnancy was assessed (R2 = 0.33, p < 0.001). The mean gestational age at birth among patients without risk factors was 38.1. Second-trimester bleeding reduced gestational age by 6.4 weeks, chorioamnionitis by 5.6 weeks, placental abruption by 5.1 weeks, PROM by 3.2 weeks and severe preeclampsia by 2.4 weeks. Conclusions: Second-trimester bleeding, chorioamnionitis, placental abruption, PROM and severe preeclampsia are ominous signs for preterm delivery among patients with MacDonald cerclage performed due to cervical incompetence.

Original languageEnglish
Pages (from-to)361-365
Number of pages5
JournalFetal Diagnosis and Therapy
Volume19
Issue number4
DOIs
StatePublished - 7 Jul 2004
Externally publishedYes

Keywords

  • Cervical incompetence
  • MacDonald cerclage
  • Preterm delivery
  • Risk factors

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