Principles of cardiovascular tissue engineering

Saray Chen, Smadar Cohen

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review


The burden of cardiovascular pathologies, such as heart failure after myocardial infarction or due to congenital heart defects, is still very high. Existing clinical therapies for these life-threatening conditions cannot regenerate and restore tissue function and provide mainly palliative treatment. This critical drawback has fueled the development of novel technologies aimed to repair or replace damaged heart tissue and correct heart defects. Such strategies, broadly termed “cardiovascular tissue engineering,” are a direct result of collaboration between researchers from various fields, such as material science, engineering, cardiovascular biology, and medicine. This chapter offers an overview of such multidisciplinary strategies, emphasizing the various concepts and major applications. The chapter could be of interest not only from an educational perspective, but also for researchers and medical professionals, offering a fresh view on novel and powerful treatment options based on tissue engineering and regeneration.

Original languageEnglish
Title of host publicationTissue Engineering, Third Edition
Number of pages32
ISBN (Electronic)9780128244593
ISBN (Print)9780323851343
StatePublished - 1 Jan 2022


  • Biomaterials
  • Blood vessels
  • Cardiovascular tissue engineering
  • Myocardial infarction
  • Myocardial regeneration
  • Vascular grafts

ASJC Scopus subject areas

  • Agricultural and Biological Sciences (all)
  • Biochemistry, Genetics and Molecular Biology (all)
  • Medicine (all)


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