Abstract
The Near Infrared spectroscopy (NIRS) is a technique, which allows measuring the oxygenation of the brain tissue.
The problem is to penetrate the brain with a light, which can cross the skin and skull and be absorbed mostly by the hemoglobin (HbO2) and the deoxyhemoglobin (Hb). The ratio of the oxygenated hemoglobin (HbO2) to the total hemoglobin (tHb=HbO2+Hb) is the regional oxygen saturation rSO2. It appears that the most suitable light is in the 650-1000 nm range of the near infrared light. In this range, there exists another absorber cytochrome oxidase (CtOx), but as its concentration is quite small, it is often neglected [60]. Instruments that take into account the CtOx use 3 different wavelengths, otherwise 2 wavelengths are used.
The problem is to penetrate the brain with a light, which can cross the skin and skull and be absorbed mostly by the hemoglobin (HbO2) and the deoxyhemoglobin (Hb). The ratio of the oxygenated hemoglobin (HbO2) to the total hemoglobin (tHb=HbO2+Hb) is the regional oxygen saturation rSO2. It appears that the most suitable light is in the 650-1000 nm range of the near infrared light. In this range, there exists another absorber cytochrome oxidase (CtOx), but as its concentration is quite small, it is often neglected [60]. Instruments that take into account the CtOx use 3 different wavelengths, otherwise 2 wavelengths are used.
| Original language | English |
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| Title of host publication | Infrared Spectroscopy |
| Subtitle of host publication | Anharmonicity of Biomolecules, Crosslinking of Biopolymers, Food Quality and Medical Applications |
| Editors | Theophile Theophanides |
| Place of Publication | Rijeka Croatia |
| Publisher | IntechOpen |
| Chapter | 3 |
| Pages | 29-62 |
| ISBN (Electronic) | 9789535150527 |
| ISBN (Print) | 9789535117377 |
| DOIs | |
| State | Published - Mar 2015 |
Publication series
| Name | Infrared Spectroscopy-Anharmonicity of Biomolecules, Crosslinking of Biopolymers, Food Quality and Medical Applications |
|---|---|
| Publisher | IntechOpen |