Probiotics for the prevention of nosocomial diarrhea in children

Iva Hojsak, Hania Szajewska, Roberto B. Canani, Alfredo Guarino, Flavia Indrio, Sanja Kolacek, Rok Orel, Raanan Shamir, Yvan Vandenplas, Johannes B. Van Goudoever, Zvi Weizman

    Research output: Contribution to journalReview articlepeer-review

    44 Scopus citations


    This document provides recommendations developed by the ESPGHAN Working Group on Probiotics and Prebiotics on the role of probiotics in the prevention of nosocomial diarrhea in children based on a systematic review of previously completed systematic reviews and of subsequently published randomized controlled trials. The quality of evidence was assessed using the Grading of Recommendations Assessment, Development and Evaluation guidelines. Recommendations were given only if at least 2 randomized controlled trials examined the same probiotic strain. Based on currently available evidence the Working Group recommends using Lactobacillus rhamnosus GG if the use of probiotics for preventing nosocomial diarrhea in children is considered.

    Original languageEnglish
    Pages (from-to)3-9
    Number of pages7
    JournalJournal of Pediatric Gastroenterology and Nutrition
    Issue number1
    StatePublished - 1 Jan 2018


    • Guideline
    • Healthcare-associated
    • Hospital-acquired
    • Microbiota
    • Randomized controlled trial
    • Systematic review

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Gastroenterology


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