Production of gamma (immune) interferon by a permanent human T-lymphocyte cell line.

J. E. Groopman, I. Nathan, D. W. Golde

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Gamma (immune, type II) interferon is an antiviral and immuno-regulatory glycoprotein usually obtained from mitogen- or antigen-induced peripheral blood or splenic mononuclear cells. A human "helper-inducer" T-lymphocyte cell line (Mo) is an inducible source of gamma interferon. Mo gamma interferon has been biochemically characterized and partially purified, and resembles the gamma interferon species derived from normal cell sources.

Original languageEnglish
Pages (from-to)219-225
Number of pages7
JournalAdvances in Experimental Medicine and Biology
Volume172
DOIs
StatePublished - 1 Jan 1984

ASJC Scopus subject areas

  • General Biochemistry, Genetics and Molecular Biology

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