Profiling the miRNA from Exosomes of Non-Pigmented Ciliary Epithelium-Derived Identifies Key Gene Targets Relevant to Primary Open-Angle Glaucoma

Keyphrases

• Oxidative Stress 100%
• Exosomes 100%
• MicroRNA 100%
• Gene Targeting 100%
• Primary Open-angle Glaucoma 100%
• Non-pigmented Ciliary Epithelium 100%
• Trabecular Meshwork 66%
• Aqueous Humor 50%
• Pigmentary 50%
• Ciliary Epithelium 50%
• Prediction Analysis 33%
• Pathway Prediction 33%
• Molecular Mechanism 16%
• Signaling Events 16%
• Threonine 16%
• Oxidative Damage 16%
• Major Constituents 16%
• Insults 16%
• Anterior Chamber 16%
• Intraocular Pressure 16%
• Cargo 16%
• Keap1-Nrf2 16%
• Elevated Intraocular Pressure 16%
• MiRNA Microarray 16%
• Chronic Oxidative Stress 16%
• ChIP-seq Analysis 16%
• Acute Oxidative Stress 16%
• Aqueous Humor Drainage 16%
• Glycogen Synthase kinase-3β (GSK-3β) 16%
• Stress Oxidative 16%
• MiR-200 16%
• RNA Exosome 16%
• Drainage Pressure 16%
• Outflow Pathway 16%
• Microarray chip 16%

Neuroscience

• MicroRNA 100%
• Open-Angle Glaucoma 100%
• Oxidative Stress 87%
• Aqueous Humor 50%
• Trabecular Meshwork 50%
• Intraocular Pressure 25%
• Gene Delivery 12%
• Serine 12%
• Threonine 12%
• Microarrays 12%
• Transcription Factor Nrf2 12%

Biochemistry, Genetics and Molecular Biology

• MicroRNA 100%
• Oxidative Stress 87%
• Humor 37%
• Intraocular Pressure 25%
• Gene Targeting 12%
• Microarrays 12%
• Target Cell 12%
• Serine 12%
• Threonine 12%
• Transcription Factor Nrf2 12%
• Aqueous Humor Flow 12%
• GSK3B 12%