TY - JOUR
T1 - Prognostic impact of sleep duration and sleep efficiency on mortality in patients with chronic heart failure.
AU - Reinhard, Wibke
AU - Plappert, Nina
AU - Zeman, Florian
AU - Hengstenberg, Christian
AU - Riegger, Günter
AU - Novack, Victor
AU - Maimon, Nimrod
AU - Pfeifer, Michael
AU - Arzt, Michael
PY - 2013/1/1
Y1 - 2013/1/1
N2 - Both short and long self-reported sleep duration (SDSR) has been linked to increased mortality. Our analysis tested the hypothesis that long SDSR is paralleled by impaired objective sleep efficiency (SEPSG) measured by polysomnography (PSG) and that impaired SEPSG is a risk factor for death in patients with chronic heart failure (CHF). SDSR and SEPSG were assessed by standardized questionnaire and PSG in 188 consecutive CHF patients (age range, 63±10 year; left ventricular ejection fraction, 34±10%) admitted to the Sleep Center of the University Hospital Regensburg between 1/2002 and 12/2009. The mean follow-up period was 44±26 months. SEPSG in CHF patients from the highest quintile of SDSR (≥9h) was significantly lower compared with the middle quintile (7.25-8h; 71±15% vs 77%±11%; p=0.032) and similar to the lowest quintile (≤5.75h; 71±15% vs 71±16%, p=0.950). SEPSG is an independent predictor for death in the multivariable model after accounting for the significant confounders age, left ventricular ejection fraction, cause of CHF, and NYHA class (hazard ratio [HR] per 5% increase, 0.85; 95% confidence interval [CI], 0.77-0.93; p<0.001). Data indicate that subjective long sleepers with CHF have poor sleep efficiency. Objectively measured SEPSG strongly predicts mortality in CHF patients, underscoring the importance of objective assessment of sleep.
AB - Both short and long self-reported sleep duration (SDSR) has been linked to increased mortality. Our analysis tested the hypothesis that long SDSR is paralleled by impaired objective sleep efficiency (SEPSG) measured by polysomnography (PSG) and that impaired SEPSG is a risk factor for death in patients with chronic heart failure (CHF). SDSR and SEPSG were assessed by standardized questionnaire and PSG in 188 consecutive CHF patients (age range, 63±10 year; left ventricular ejection fraction, 34±10%) admitted to the Sleep Center of the University Hospital Regensburg between 1/2002 and 12/2009. The mean follow-up period was 44±26 months. SEPSG in CHF patients from the highest quintile of SDSR (≥9h) was significantly lower compared with the middle quintile (7.25-8h; 71±15% vs 77%±11%; p=0.032) and similar to the lowest quintile (≤5.75h; 71±15% vs 71±16%, p=0.950). SEPSG is an independent predictor for death in the multivariable model after accounting for the significant confounders age, left ventricular ejection fraction, cause of CHF, and NYHA class (hazard ratio [HR] per 5% increase, 0.85; 95% confidence interval [CI], 0.77-0.93; p<0.001). Data indicate that subjective long sleepers with CHF have poor sleep efficiency. Objectively measured SEPSG strongly predicts mortality in CHF patients, underscoring the importance of objective assessment of sleep.
UR - http://www.scopus.com/inward/record.url?scp=84893355428&partnerID=8YFLogxK
U2 - 10.1016/j.sleep.2012.12.014
DO - 10.1016/j.sleep.2012.12.014
M3 - Article
C2 - 23628241
AN - SCOPUS:84893355428
SN - 1389-9457
VL - 14
SP - 502
EP - 509
JO - Sleep Medicine
JF - Sleep Medicine
IS - 6
ER -