Proof of concept: Comparative accuracy of semiautomated VR modeling for volumetric analysis of the heart ventricles

David Yogev, Shai Tejman-Yarden, Omer Feinberg, Yisrael Parmet, Tomer Goldberg, Shay Ilouz, Netanel Nagar, Dor Freidin, Oliana Vazgovsky, Sumit Chatterji, Yishay Salem, Uriel Katz, Orly Goitein

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Introduction: Simpson's rule is generally used to estimate cardiac volumes. By contrast, modern methods such as Virtual Reality (VR) utilize mesh modeling to present the object's surface spatial structure, thus enabling intricate volumetric calculations. In this study, two types of semiautomated VR models for cardiac volumetric analysis were compared to the standard Philips dedicated cardiac imaging platform (PDP) which is based on Simpson's rule calculations. Methods: This retrospective report examined the cardiac computed tomography angiography (CCTA) of twenty patients with atrial fibrillation obtained prior to a left atrial appendage occlusion procedure. We employed two VR models to evaluate each CCTA and compared them to the PDP: a VR model with Philips-similar segmentations (VR-PS) that included the trabeculae and the papillary muscles within the luminal volume, and a VR model that only included the inner blood pool (VR-IBP). Results: Comparison of the VR-PS and the PDP left ventricle (LV) volumes demonstrated excellent correlation with a ρc of 0.983 (95% CI 0.96, 0.99), and a small mean difference and range. The calculated volumes of the right ventricle (RV) had a somewhat lower correlation of 0.89 (95% CI 0.781, 0.95), a small mean difference, and a broader range. The VR-IBP chamber size estimations were significantly smaller than the estimates based on the PDP. Discussion: Simpson's rule and polygon summation algorithms produce similar results in normal morphological LVs. However, this correlation failed to emerge when applied to RVs and irregular chambers. Conclusions: The findings suggest that the polygon summation method is preferable for RV and irregular LV volume and function calculations.

Original languageEnglish
Article numbere11250
Issue number11
StatePublished - 1 Nov 2022


  • Heart chambers
  • Polygon summation
  • Virtual reality
  • Volumetric analysis

ASJC Scopus subject areas

  • General


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