Propagation of structured light through tissue-mimicking phantoms

ALESSIA SUPRANO; TAIRA GIORDANI; ILARIA GIANANI; NICOLÓ SPAGNOLO; KATJA PINKER; JUDY KUPFERMAN; SHLOMI ARNON; UWE KLEMM; DIMITRIS GORPAS; VASILIS NTZIACHRISTOS; FABIO SCIARRINO

doi:10.1364/OE.402467

Propagation of structured light through tissue-mimicking phantoms

ALESSIA SUPRANO, TAIRA GIORDANI, ILARIA GIANANI, NICOLÓ SPAGNOLO, KATJA PINKER, JUDY KUPFERMAN, SHLOMI ARNON, UWE KLEMM, DIMITRIS GORPAS, VASILIS NTZIACHRISTOS, FABIO SCIARRINO

Department of Electrical & Computer Engineering

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Optical interrogation of tissues is broadly considered in biomedical applications. Nevertheless, light scattering by tissue limits the resolution and accuracy achieved when investigating sub-surface tissue features. Light carrying optical angular momentum or complex polarization profiles, offers different propagation characteristics through scattering media compared to light with unstructured beam profiles. Here we discuss the behaviour of structured light scattered by tissue-mimicking phantoms. We study the spatial and the polarization profile of the scattered modes as a function of a range of optical parameters of the phantoms, with varying scattering and absorption coefficients and of different lengths. These results show the non-trivial trade-off between the advantages of structured light profiles and mode broadening, stimulating further investigations in this direction.

Original language	English
Pages (from-to)	35427-35437
Number of pages	11
Journal	Optics Express
Volume	28
Issue number	24
DOIs	https://doi.org/10.1364/OE.402467
State	Published - 23 Nov 2020

ASJC Scopus subject areas

Atomic and Molecular Physics, and Optics

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title = "Propagation of structured light through tissue-mimicking phantoms",

abstract = "Optical interrogation of tissues is broadly considered in biomedical applications. Nevertheless, light scattering by tissue limits the resolution and accuracy achieved when investigating sub-surface tissue features. Light carrying optical angular momentum or complex polarization profiles, offers different propagation characteristics through scattering media compared to light with unstructured beam profiles. Here we discuss the behaviour of structured light scattered by tissue-mimicking phantoms. We study the spatial and the polarization profile of the scattered modes as a function of a range of optical parameters of the phantoms, with varying scattering and absorption coefficients and of different lengths. These results show the non-trivial trade-off between the advantages of structured light profiles and mode broadening, stimulating further investigations in this direction.",

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AU - SUPRANO, ALESSIA

AU - GIORDANI, TAIRA

AU - GIANANI, ILARIA

AU - SPAGNOLO, NICOLÓ

AU - PINKER, KATJA

AU - KUPFERMAN, JUDY

AU - ARNON, SHLOMI

AU - KLEMM, UWE

AU - GORPAS, DIMITRIS

AU - NTZIACHRISTOS, VASILIS

AU - SCIARRINO, FABIO

PY - 2020/11/23

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AB - Optical interrogation of tissues is broadly considered in biomedical applications. Nevertheless, light scattering by tissue limits the resolution and accuracy achieved when investigating sub-surface tissue features. Light carrying optical angular momentum or complex polarization profiles, offers different propagation characteristics through scattering media compared to light with unstructured beam profiles. Here we discuss the behaviour of structured light scattered by tissue-mimicking phantoms. We study the spatial and the polarization profile of the scattered modes as a function of a range of optical parameters of the phantoms, with varying scattering and absorption coefficients and of different lengths. These results show the non-trivial trade-off between the advantages of structured light profiles and mode broadening, stimulating further investigations in this direction.

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Propagation of structured light through tissue-mimicking phantoms

Abstract

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