Keyphrases
Alzheimer's Disease
100%
Calcium Dysregulation
100%
Lysosomal Proteolysis
100%
Mishandling
100%
Alzheimer's Disease Model
42%
Lysosome
42%
Ryanodine Receptor
42%
Ca2+ Release
28%
Alzheimer's Disease Patient
28%
Induced Neurons
28%
Lysosomal Acidification
28%
Proteolytic Activity
28%
Ca2+ Signaling
28%
Intracellular Protein
28%
Protein Aggregates
28%
Vacuolar H+-ATPase (V-ATPase)
28%
Clinically Significant
14%
Cellular Processes
14%
Neurodegenerative Diseases
14%
Cognitive Deficits
14%
Synaptic Dysfunction
14%
Alzheimer's Disease Pathology
14%
Disease-associated
14%
Phosphorylated tau
14%
Endoplasmic Reticulum
14%
Therapeutic Intervention
14%
Cell Debris
14%
Signaling Cascades
14%
Autophagic
14%
Reduced Expression
14%
Optical Imaging
14%
Intracellular Calcium
14%
Autophagosome
14%
Cellular Signaling
14%
Model Cell
14%
Motor Neuron Disease
14%
Fluorescent Sensor
14%
Pathogenic Proteins
14%
Proton Pump
14%
Digestive Capacity
14%
Model Neurons
14%
Dantrolene
14%
Autophagic Clearance
14%
Neuritic Dystrophy
14%
Human Neurons
14%
ATPase Subunits
14%
Proteinopathy
14%
Murine Neurons
14%
Biosensor Imaging
14%
IPSC-derived Neurons
14%
Negative Allosteric Modulator
14%
Acidification Rate
14%
Biochemistry, Genetics and Molecular Biology
Protein Catabolism
100%
Lysosome
100%
Ryanodine Receptor
100%
V-ATPase
66%
Mouse Model
66%
Calcium Signaling
66%
Animal Model
33%
Signal Transduction
33%
Tau
33%
Autophagosome
33%
Calcium Cell Level
33%
Proton Pump
33%
Induced Pluripotent Stem Cell
33%
Optical Imaging
33%
Proteinopathy
33%