Abstract
Background: Large epidemiological studies show reduced cancer rate in coffee drinking subjects. It was hypothesized that the protective effect of caffeine is related to its antagonist properties on adenosine A2A receptor (A2AR). Adenosine accumulates in solid tumors and has been shown to stimulate angiogenesis and to inhibit the activity of immune cells mainly through A2AR. Here, we examined the effect of caffeine on tumor development and immune surveillance.
Original language | English |
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Pages (from-to) | 84-84 |
Number of pages | 1 |
Journal | Cytokine |
Volume | 56 |
Issue number | 1 |
DOIs | |
State | Published - Oct 2011 |