Abstract
BACKGROUND: Crohn’s disease (CD) patients all experience psychological distress, but its characteristics are incompletely understood. We report an in-depth cross-sectional study in 297 patients. METHODS: The Brief Symptom Inventory (BSI, Derogatis 1983) measures psychological distress: 59 items assess depression, somatization, obsession-compulsive, interpersonal sensitivity, anxiety, hostility, phobic anxiety, paranoid ideation and psychoticism. BSI
summary scores are: General Severity Index (GSI, mean of category scores, range 0-4), Positive Symptom Total (PST, sum of recorded symptoms) and Positive Symptom Distress Index (PSDI, summated item values divided by PST); higher
scores imply more distress. Patients completed demographics, Patient-Harvey-Bradshaw Index (P-HBI), BSI, Family Assessment Device (FAD, measures family functioning) and Multidimensional Scale of Perceived Social Support (MSPSS, measures social support). RESULTS: GSI scores were similarly elevated in men 1.0+8.7 and women.0+8.8, but significantly higher in single 1.2+8 vs coupled
.9+.8, smokers 1.3+.8 vs non-smokers .9+.8 and nonworking 1.2+.9 vs working .9+.7. PST scores were: men 25.8+15.2 vs women 26.4+13.7 (ns), single 29.614.0 vs coupled 23.1+14.0, smokers 30.3+14.0 vs non-smokers
25.0+14.4 and non-working 29.3+14.6 vs working 24.4+18.8. PSDI scores were: men 1.8+1.7 vs women 1.8+1.7 (ns), single 1.9+.6 vs coupled 1.7+.6, smokers 2.0.6 vs non-smokers 1.7+.6, and non-working 1.9.7 vs working 1.7.6. GSI, PST and PSDI scores correlated significantly with age, economic status, P-HBI, FAD and MSPSS (Table 1). Multivariate regression analysis identified age, economic status, FAD, MSPSS, P-HBI as predictors of distress (Table 2). Notably, gender did not predict distress.
CONCLUSION: Psychological distress is increased in CD and predicted by age, economic status, family relationship, social support and disease activity. Caregivers should incorporate these findings in patient management.
summary scores are: General Severity Index (GSI, mean of category scores, range 0-4), Positive Symptom Total (PST, sum of recorded symptoms) and Positive Symptom Distress Index (PSDI, summated item values divided by PST); higher
scores imply more distress. Patients completed demographics, Patient-Harvey-Bradshaw Index (P-HBI), BSI, Family Assessment Device (FAD, measures family functioning) and Multidimensional Scale of Perceived Social Support (MSPSS, measures social support). RESULTS: GSI scores were similarly elevated in men 1.0+8.7 and women.0+8.8, but significantly higher in single 1.2+8 vs coupled
.9+.8, smokers 1.3+.8 vs non-smokers .9+.8 and nonworking 1.2+.9 vs working .9+.7. PST scores were: men 25.8+15.2 vs women 26.4+13.7 (ns), single 29.614.0 vs coupled 23.1+14.0, smokers 30.3+14.0 vs non-smokers
25.0+14.4 and non-working 29.3+14.6 vs working 24.4+18.8. PSDI scores were: men 1.8+1.7 vs women 1.8+1.7 (ns), single 1.9+.6 vs coupled 1.7+.6, smokers 2.0.6 vs non-smokers 1.7+.6, and non-working 1.9.7 vs working 1.7.6. GSI, PST and PSDI scores correlated significantly with age, economic status, P-HBI, FAD and MSPSS (Table 1). Multivariate regression analysis identified age, economic status, FAD, MSPSS, P-HBI as predictors of distress (Table 2). Notably, gender did not predict distress.
CONCLUSION: Psychological distress is increased in CD and predicted by age, economic status, family relationship, social support and disease activity. Caregivers should incorporate these findings in patient management.
| Original language | English GB |
|---|---|
| Pages (from-to) | S49-S49 |
| Journal | Gastroenterology |
| Volume | 154 |
| Issue number | 1 |
| State | Published - Jan 2018 |