Psychopathology in pediatric complex partial and primary generalized epilepsy

Rochelle Caplan, Shoshana Arbelle, Wagdan Magharious, Donald Guthrie, Scott Komo, W. Donald Shields, Sirichai Chayasirisobhon, Rebecca Hansen

    Research output: Contribution to journalArticlepeer-review

    66 Scopus citations


    Structured psychiatric interviews were administered to 60 children with complex partial seizure disorder (CPS), 40 children with primary generalized epilepsy with absences (PGE), and 48 control children, aged 5 to 16 years. Significantly more patients with epilepsy had psychiatric diagnoses compared with the control children. There were no statistically significant differences, however, in the number of patients with CPS and PGE with psychiatric diagnoses. Other than a schizophrenia-like psychosis found only in the patients with CPS, the two groups of patients had similar psychiatric diagnoses. The presence of psychopathology was related to significantly lower IQ scores and socioeconomic status, but not to seizure-related factors. These findings suggest that the psychopathology of children with CPS and PGE reflects different subtle neuropsychological deficits.

    Original languageEnglish
    Pages (from-to)805-811
    Number of pages7
    JournalDevelopmental Medicine and Child Neurology
    Issue number12
    StatePublished - 1 Jan 1998

    ASJC Scopus subject areas

    • Pediatrics, Perinatology, and Child Health
    • Developmental Neuroscience
    • Clinical Neurology


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