Abstract
The Trofimov reaction was extended to methyl aryl ketoximes with substituents in the benzene ring that are unstable with respect to the action of a strongly basic medium. The corresponding pyrroles and their 1-vinyl derivatives were obtained. 4-Nitroacetophenone oxime, from which only 2-phenyl- and 1-vinyl-2-phenylpyrrole were obtained, and 4-bromoacetophenone oxime, the reaction of which leads to the formation of 1-vinyl-2-(4-vinyloxyphenyl)pyrrole in addition to the principal 2-(4-bromophenyl)pyrrole, constituted exceptions.
Original language | English |
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Pages (from-to) | 151-155 |
Number of pages | 5 |
Journal | Chemistry of Heterocyclic Compounds |
Volume | 27 |
Issue number | 2 |
DOIs | |
State | Published - 1 Feb 1991 |
Externally published | Yes |
ASJC Scopus subject areas
- Organic Chemistry