Pyrroles from ketoximes and acetylene. 44. Methyl aryl ketoximes with reactive substituents

S. E. Korostova, S. G. Shevchenko, M. V. Sigalov

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

The Trofimov reaction was extended to methyl aryl ketoximes with substituents in the benzene ring that are unstable with respect to the action of a strongly basic medium. The corresponding pyrroles and their 1-vinyl derivatives were obtained. 4-Nitroacetophenone oxime, from which only 2-phenyl- and 1-vinyl-2-phenylpyrrole were obtained, and 4-bromoacetophenone oxime, the reaction of which leads to the formation of 1-vinyl-2-(4-vinyloxyphenyl)pyrrole in addition to the principal 2-(4-bromophenyl)pyrrole, constituted exceptions.

Original languageEnglish
Pages (from-to)151-155
Number of pages5
JournalChemistry of Heterocyclic Compounds
Volume27
Issue number2
DOIs
StatePublished - 1 Feb 1991
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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