Quality control parameters for dried aqueous extract of Guduchi (Tinospora Cordifolia (Willd.) Miers.)

S. N. Dhundi, P. Yadav, C. R. Harisha, V. J. Shukla, B. J. Patgiri, P. K. Prajapati

Research output: Contribution to journalArticlepeer-review

Abstract

Tinospora cordifolia (Willd.) Miers., commonly known as Guduchi, is widely used in Ayurveda for the treatment of wide range of diseases and as a Rasayana (rejuvenator) herb. It is used for its immunomodulatory, anti-inflammatory, antidiabetic, anti-hyperglycemic, hypoglycemic, anti-oxidant and febrifugal activities. Guduchi Ghana (dried aqueous extract) of drug is prescribed in fevers, diabetes, dyspepsia, jaundice, urinary problems, skin diseases, chronic diarrhoea and dysentery. This paper deals with detailed quality control parametric analysis of Guduchi Ghana. The diagnostic characters of this plant include simple and compound starch grains, prismatic crystals of calcium oxalate, non-chlorenchymatus parenchyma cells. Physicochemical parameters of Ghana revealed pH 4.4, moisture contain not more than 10.05, ash value not more than 9.88 % w/w, acid insoluble extract not less than 1.10 %w/w, water soluble extract not less than 56.08% and alcohol soluble extract not less than 49.08 % w/w. HPTLC showed 4 and 2 spots in 254 and 366 nm respectively. Thus these may be considered as quality control parameters for the Guduchi Ghana.

Original languageEnglish
Pages (from-to)72-76
Number of pages5
JournalInternational Journal of Pharmaceutical Research
Volume4
Issue number2
StatePublished - 1 Dec 2012
Externally publishedYes

Keywords

  • Guduchi Ghana
  • HPTLC

ASJC Scopus subject areas

  • Pharmacology, Toxicology and Pharmaceutics (all)

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