Radioiodine Uptake in Incidentally Detected Neuroendocrine Tumor Correlative Imaging with FDG PET/CT and 68Ga-DOTATATE PET/CT

Nir Hod, Sophie Lantsberg, Daniel Levin

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Radioiodine whole-body scintigraphy has long been used for detection of differentiated thyroid carcinoma with high avidity in functioning thyroid tissues. However, uptake is not completely specific, and "false-positive"uptake in nonthyroidal tumors have rarely been reported. Herein, we present a case of incidentally detected neuroendocrine tumor showing high radioiodine uptake initially suspected to be thyroid metastasis. Correlative imaging with FDG PET/CT and 68Ga-DOTATATE PET/CT is presented, and literature survey is discussed. We conclude that neuroendocrine tumor should be added to the reported list of neoplasms that can show "false-positive"uptake representing a potential interpretative pitfall.

Original languageEnglish
Pages (from-to)e643-e646
JournalClinical Nuclear Medicine
Volume47
Issue number10
DOIs
StatePublished - Oct 2022

Keywords

  • Ga-DOTATATE PET/CT
  • differentiated thyroid carcinoma
  • false-positive uptake
  • FDG PET/CT
  • neuroendocrine tumor
  • radioiodine I whole-body scintigraphy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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