Rapid lithiumization in acute manic patients

D. G. Moscovich; B. Shapira; B. Lerer; R. H. Belmaker

doi:10.1002/hup.470070508

Rapid lithiumization in acute manic patients

D. G. Moscovich, B. Shapira, B. Lerer, R. H. Belmaker

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

Nine patients with acute mania were treated with high‐dose lithium therapy and daily blood level monitoring for the first 3 days of treatment. Rapid reduction in psychopathology was seen. It is possible that the delay of 7–10 days in clinical response to usual lithium treatment may be partially pharmacokinetic, and that high‐dose lithium loading at the onset of treatment of mania may reduce the need for neuroleptic co‐treatment.

Original language	English
Pages (from-to)	343-345
Number of pages	3
Journal	Human Psychopharmacology
Volume	7
Issue number	5
DOIs	https://doi.org/10.1002/hup.470070508
State	Published - 1 Jan 1992
Externally published	Yes

Keywords

Lithium
high‐dose
mania

ASJC Scopus subject areas

Neurology
Clinical Neurology
Psychiatry and Mental health
Pharmacology (medical)

Access to Document

10.1002/hup.470070508

Cite this

@article{d08991449a514b2eb386f513c8a9bc38,

title = "Rapid lithiumization in acute manic patients",

abstract = "Nine patients with acute mania were treated with high‐dose lithium therapy and daily blood level monitoring for the first 3 days of treatment. Rapid reduction in psychopathology was seen. It is possible that the delay of 7–10 days in clinical response to usual lithium treatment may be partially pharmacokinetic, and that high‐dose lithium loading at the onset of treatment of mania may reduce the need for neuroleptic co‐treatment.",

keywords = "Lithium, high‐dose, mania",

author = "Moscovich, {D. G.} and B. Shapira and B. Lerer and Belmaker, {R. H.}",

year = "1992",

month = jan,

day = "1",

doi = "10.1002/hup.470070508",

language = "English",

volume = "7",

pages = "343--345",

journal = "Human Psychopharmacology",

issn = "0885-6222",

publisher = "John Wiley and Sons Ltd",

number = "5",

}

TY - JOUR

T1 - Rapid lithiumization in acute manic patients

AU - Moscovich, D. G.

AU - Shapira, B.

AU - Lerer, B.

AU - Belmaker, R. H.

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Nine patients with acute mania were treated with high‐dose lithium therapy and daily blood level monitoring for the first 3 days of treatment. Rapid reduction in psychopathology was seen. It is possible that the delay of 7–10 days in clinical response to usual lithium treatment may be partially pharmacokinetic, and that high‐dose lithium loading at the onset of treatment of mania may reduce the need for neuroleptic co‐treatment.

AB - Nine patients with acute mania were treated with high‐dose lithium therapy and daily blood level monitoring for the first 3 days of treatment. Rapid reduction in psychopathology was seen. It is possible that the delay of 7–10 days in clinical response to usual lithium treatment may be partially pharmacokinetic, and that high‐dose lithium loading at the onset of treatment of mania may reduce the need for neuroleptic co‐treatment.

KW - Lithium

KW - high‐dose

KW - mania

UR - http://www.scopus.com/inward/record.url?scp=0027077497&partnerID=8YFLogxK

U2 - 10.1002/hup.470070508

DO - 10.1002/hup.470070508

M3 - Article

AN - SCOPUS:0027077497

SN - 0885-6222

VL - 7

SP - 343

EP - 345

JO - Human Psychopharmacology

JF - Human Psychopharmacology

IS - 5

ER -

Rapid lithiumization in acute manic patients

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this