Rapid lithiumization in acute manic patients

D. G. Moscovich, B. Shapira, B. Lerer, R. H. Belmaker

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

Nine patients with acute mania were treated with high‐dose lithium therapy and daily blood level monitoring for the first 3 days of treatment. Rapid reduction in psychopathology was seen. It is possible that the delay of 7–10 days in clinical response to usual lithium treatment may be partially pharmacokinetic, and that high‐dose lithium loading at the onset of treatment of mania may reduce the need for neuroleptic co‐treatment.

Original languageEnglish
Pages (from-to)343-345
Number of pages3
JournalHuman Psychopharmacology
Volume7
Issue number5
DOIs
StatePublished - 1 Jan 1992
Externally publishedYes

Keywords

  • Lithium
  • high‐dose
  • mania

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