TY - JOUR
T1 - Re-Treatment by Flap Relift Versus Surface Ablation after Myopic Laser in Situ Keratomileusis
AU - Hecht, Idan
AU - Mimouni, Michael
AU - Rabina, Gilad
AU - Kaiserman, Igor
N1 - Publisher Copyright:
© 2020 Lippincott Williams and Wilkins. All rights reserved.
PY - 2020/4/1
Y1 - 2020/4/1
N2 - Purpose:To compare clinical outcomes of patients undergoing first re-treatment by flap relift with those re-treated by surface ablation on the flap after an initial myopic laser-assisted in situ keratomileusis (LASIK) procedure.Methods:This is a retrospective cohort analysis of consecutive patients who underwent myopic LASIK and required re-treatment between January 2007 and December 2016. Cases re-treated by flap relift were propensity score matched with cases re-treated by surface ablation, and clinical outcomes were compared. One eye from each patient was included.Results:A total of 1,234 out of 21,191 cases required re-treatment after myopic LASIK during the follow-up period. Surface ablation was performed in 75% of cases and relift in 25%. Patients re-treated by surface ablation were more commonly male (61.8% vs. 48.1%, P < 0.001), were younger (33.2 ± 7.8 vs. 35.2 ± 10 years, P = 0.005), and had thinner corneas (483 ± 46 vs. 502 ± 43 m, P < 0.001). Propensity score matching was performed for 416 eyes (208 from each group). After matching, differences in baseline characteristics became nonsignificant (P > 0.05). Cases re-treated by surface ablation had a worse safety index (0.98 ± 0.12 vs. 1.02 ± 0.17, P = 0.049), yet better predictability (0.14 ± 0.6 vs. 0.35 ± 0.5 diopters of deviation, P = 0.009), a similar efficacy index (0.92 ± 0.2 vs. 0.93 ± 0.3, P = 0.814), higher rates of haze (5.8% vs. 0.5%, P = 0.002), and a lower risk for epithelial ingrowth (0.5% vs. 8.2%, P < 0.001).Conclusions:Re-treatment after myopic LASIK with surface ablation resulted in worse safety and higher rates of haze, yet more predictable outcomes and reduced ingrowth rates, compared with re-treatment with flap relift.
AB - Purpose:To compare clinical outcomes of patients undergoing first re-treatment by flap relift with those re-treated by surface ablation on the flap after an initial myopic laser-assisted in situ keratomileusis (LASIK) procedure.Methods:This is a retrospective cohort analysis of consecutive patients who underwent myopic LASIK and required re-treatment between January 2007 and December 2016. Cases re-treated by flap relift were propensity score matched with cases re-treated by surface ablation, and clinical outcomes were compared. One eye from each patient was included.Results:A total of 1,234 out of 21,191 cases required re-treatment after myopic LASIK during the follow-up period. Surface ablation was performed in 75% of cases and relift in 25%. Patients re-treated by surface ablation were more commonly male (61.8% vs. 48.1%, P < 0.001), were younger (33.2 ± 7.8 vs. 35.2 ± 10 years, P = 0.005), and had thinner corneas (483 ± 46 vs. 502 ± 43 m, P < 0.001). Propensity score matching was performed for 416 eyes (208 from each group). After matching, differences in baseline characteristics became nonsignificant (P > 0.05). Cases re-treated by surface ablation had a worse safety index (0.98 ± 0.12 vs. 1.02 ± 0.17, P = 0.049), yet better predictability (0.14 ± 0.6 vs. 0.35 ± 0.5 diopters of deviation, P = 0.009), a similar efficacy index (0.92 ± 0.2 vs. 0.93 ± 0.3, P = 0.814), higher rates of haze (5.8% vs. 0.5%, P = 0.002), and a lower risk for epithelial ingrowth (0.5% vs. 8.2%, P < 0.001).Conclusions:Re-treatment after myopic LASIK with surface ablation resulted in worse safety and higher rates of haze, yet more predictable outcomes and reduced ingrowth rates, compared with re-treatment with flap relift.
KW - LASIK
KW - efficacy index
KW - flap relift
KW - re-treatment
KW - safety index
KW - surface ablation
UR - http://www.scopus.com/inward/record.url?scp=85081943800&partnerID=8YFLogxK
U2 - 10.1097/ICO.0000000000002189
DO - 10.1097/ICO.0000000000002189
M3 - Article
C2 - 31658171
AN - SCOPUS:85081943800
SN - 0277-3740
VL - 39
SP - 443
EP - 450
JO - Cornea
JF - Cornea
IS - 4
ER -